- Virus-like Particle Display of the α-Gal Carbohydrate for Vaccination against
Virus-like Particle Display of the α-Gal Carbohydrate for Vaccination against
ACS central science (2017-10-06)
Anna Paula V Moura, Luiza C B Santos, Carlos Ramon Nascimento Brito, Edward Valencia, Caroline Junqueira, Adalberto A P Filho, Mauricio R V Sant'Anna, Nelder F Gontijo, Daniella C Bartholomeu, Ricardo T Fujiwara, Ricardo T Gazzinelli, Craig S McKay, Carlos A Sanhueza, M G Finn, Alexandre Ferreira Marques
PMID28979944
RÉSUMÉ
Secreted and surface-displayed carbohydrates are essential for virulence and viability of many parasites, including for immune system evasion. We have identified the α-Gal trisaccharide epitope on the surface of the protozoan parasites
MATÉRIAUX