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Synthesis of imidazolium-containing mono-methacrylates as polymerizable antibacterial agents for acrylic bone cements.

Journal of the mechanical behavior of biomedical materials (2017-06-12)
Wenbin Zhu, Fang Liu, Jingwei He
RÉSUMÉ

With the aim to prepare antibacterial acrylic bone cements, a series of imidazolium-containg mono-methacrylates with N-alkyl chain length varied from 10 to 18 (MEIM-x) were synthesized as polymerizable antibacterial agents through a two-step reaction. The structures of the monomers were confirmed by

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Sigma-Aldrich
2-Isocyanatoethyl methacrylate, contains ≤0.1% BHT as inhibitor, 98%
Sigma-Aldrich
1-Bromotetradecane, 97%