- Membrane dynamics of resting and internalin B-bound MET receptor tyrosine kinase studied by single-molecule tracking.
Membrane dynamics of resting and internalin B-bound MET receptor tyrosine kinase studied by single-molecule tracking.
FEBS open bio (2017-09-15)
Marie-Lena I E Harwardt, Phoebe Young, Willem M Bleymüller, Timo Meyer, Christos Karathanasis, Hartmut H Niemann, Mike Heilemann, Marina S Dietz
PMID28904870
RÉSUMÉ
The human MET receptor tyrosine kinase contributes to vertebrate development and cell proliferation. As a proto-oncogene, it is a target in cancer therapies. MET is also relevant for bacterial infection by