Aberrant expression of ZNF268 alters the growth and migration of ovarian cancer cells.

Ovarian cancer is one of the most lethal gynaecological cancers worldwide. However, the mechanisms underlying ovarian carcinogenesis are not well understood. The present study used immunostaining, western blotting and quantitative real-time PCR to demonstrate that ZNF268 is overexpressed in human ovarian carcinomas. ZNF268-knockdown increased the viability, colony formation and growth of