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Merck

[Preparation and antileukemic activity of quinolizidinylalkyl-derivatives of 4-aminoquinoline and 9-aminoacridine].

Bollettino chimico farmaceutico (1989-06-01)
C Boido Canu, V Boido, F Sparatore
RÉSUMÉ

By reacting three quinolizidinylalkylamines with 4,7-dichloroquinoline and 6,9-dichloro-2-methoxyacridine six derivatives of 4-aminoquinoline and 9-aminoacridine were obtained. These compounds, which are of interest as potential antibacterial, antiprotozoarian, anti-helminthic and antitumoral agents, so far have been tested against lymphocytic leukemia P 388 and found to be inactive.

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Sigma-Aldrich
6,9-Dichloro-2-methoxyacridine, 97%