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Merck

Relaxivity control of magnetic nanoclusters for efficient magnetic relaxation switching assay.

Chemical communications (Cambridge, England) (2012-10-27)
Jinmyung Cha, Yong-Su Kwon, Tae-Jong Yoon, Jin-Kyu Lee
RÉSUMÉ

50 nm Magnetic nanocluster (MNC) was deliberately selected as an efficient probe for the magnetic relaxation switching (MRSw) assay. After surface modification of MNCs with poly(acrylic acid) to give PAA-MNCs, and employing streptavidin-biotin interactions for the MRSw assay model, a few tenths pM concentration of strepavidin could be determined.

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