- A universal platform for amplified multiplexed DNA detection based on exonuclease III-coded magnetic microparticle probes.
A universal platform for amplified multiplexed DNA detection based on exonuclease III-coded magnetic microparticle probes.
Chemical communications (Cambridge, England) (2012-06-21)
Ming Luo, Xia Xiang, Dongshan Xiang, Si Yang, Xinghu Ji, Zhike He
PMID22714662
RÉSUMÉ
An amplified multiplexed DNA detection biosensor has been developed, which combines the unique cleavage function of exonuclease III (Exo III) with the separating ability of magnetic microparticles (MMPs). By using different fluorophores, the multiplexed detection of DNA is demonstrated.