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Correlations of Fat Content in Human Milk with Fat Droplet Size and Phospholipid Species.

Molecules (Basel, Switzerland) (2021-04-04)
Beibei Duan, Eun-Sik Hong, Jung-Ah Shin, Yan Qin, Jeung-Hee Lee, Chi-Woo Lee, Ki-Teak Lee
RÉSUMÉ

Fat globule size and phospholipid (PL) content in human milk (HM) were investigated. HM was classified into three groups depending on fat content (A < B < C). PL content (mg/100 g HM) was significantly higher in the C group (p < 0.05), indicating its positive relationship with HM fat content. When the PL content was normalized (mg/g fat), that of group A was significantly higher (p < 0.05) and fat droplet size in group C was slightly larger, suggesting that HM fat content is affected by fat droplet numbers to a larger extent than by fat droplet size. A correlation between PC and SM content in HM was observed regardless of fat content, while correlation between PE and either PC or SM increased in the order of C > B > A, hence the composition and content of PL species in HM varied according to its fat content.

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Sigma-Aldrich
L-α-Lysophosphatidylcholine, egg yolk, ≥99.0% (TLC)
Sigma-Aldrich
Sphingomyelin, from chicken egg yolk, ≥98.0% (TLC)