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BCR096

Dibenzo[a,l]pyrene

BCR®, certified reference material

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About This Item

Formule empirique (notation de Hill):
C24H14
Numéro CAS:
Poids moléculaire :
302.37
Numéro Beilstein :
2054068
Numéro MDL:
Code UNSPSC :
41116107
ID de substance PubChem :
Nomenclature NACRES :
NA.24

Qualité

certified reference material

Agence

BCR®

Fabricant/nom de marque

JRC

Technique(s)

HPLC: suitable
gas chromatography (GC): suitable

Format

neat

Température de stockage

2-8°C

Chaîne SMILES 

c1ccc2c(c1)cc3ccc4cccc5c6ccccc6c2c3c45

InChI

1S/C24H14/c1-2-8-18-16(6-1)14-17-13-12-15-7-5-11-20-19-9-3-4-10-21(19)24(18)23(17)22(15)20/h1-14H

Clé InChI

JNTHRSHGARDABO-UHFFFAOYSA-N

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Remarque sur l'analyse

For more information please see:
BCR096

Informations légales

BCR is a registered trademark of European Commission

Pictogrammes

Health hazardCorrosion

Mention d'avertissement

Danger

Mentions de danger

Classification des risques

Carc. 1B - Eye Dam. 1 - Muta. 2

Code de la classe de stockage

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


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Lisbeth K Siddens et al.
Toxicology and applied pharmacology, 264(3), 377-386 (2012-09-01)
The polycyclic aromatic hydrocarbon (PAH), benzo[a]pyrene (BaP), was compared to dibenzo[def,p]chrysene (DBC) and combinations of three environmental PAH mixtures (coal tar, diesel particulate and cigarette smoke condensate) using a two stage, FVB/N mouse skin tumor model. DBC (4nmol) was most
David J Castro et al.
Carcinogenesis, 30(2), 315-320 (2008-12-17)
The carcinogenic potential of dibenzo[a,l]pyrene (DBP) has been well characterized in numerous animal models. We have previously documented that a single dose of 15 mg/Kg DBP to pregnant mice late in gestation (GD 17) produces an aggressive T-cell lymphoma as
George S Bailey et al.
Chemical research in toxicology, 22(7), 1264-1276 (2009-05-20)
Assessment of human cancer risk from animal carcinogen studies is severely limited by inadequate experimental data at environmentally relevant exposures and by procedures requiring modeled extrapolations many orders of magnitude below observable data. We used rainbow trout, an animal model
Susan Ritger Crowell et al.
Toxicology and applied pharmacology, 257(3), 365-376 (2011-10-18)
Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous environmental contaminants generated as byproducts of natural and anthropogenic combustion processes. Despite significant public health concern, physiologically based pharmacokinetic (PBPK) modeling efforts for PAHs have so far been limited to naphthalene, plus simpler PK
Fredine T Lauer et al.
Journal of toxicology and environmental health. Part A, 76(1), 16-24 (2012-11-16)
Dibenzo[def,p]chrysene (DBC) is a potent environmental carcinogen in rodents, fish, and human cells examined in culture. There are numerous similarities between the patterns of cytochrome P-450 (P450) activation of DBC and its covalent binding to DNA and proteins with another

Articles

This application note describes the fast and efficient separation of the EU’s list of 15 + 1 polynuclear aromatic hydrocarbons (PAHs) using Ascentis® Express PAH HPLC column.

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