MABMAG-83K
MILLIPLEX® Mouse Amyloid Beta Magnetic Bead Panel - Multiplex Assay
for quantification of Aβ40 and Aβ42 in mouse serum, plasma, CSF and tissue culture samples
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About This Item
Code UNSPSC :
12161503
eCl@ss :
32161000
Nomenclature NACRES :
NA.47
Produits recommandés
Niveau de qualité
Espèces réactives
mouse
Fabricant/nom de marque
Milliplex®
assay range
accuracy: 80%
(Spike recovery for Aβ1-40)
sensitivity: 3.6 pg/mL
(A?1-40; MinDC+2SD)
sensitivity: 4.8 pg/mL
(A?1-42; MinDC+2SD)
standard curve range: 3-2500 pg/mL
(Aβ1-40)
standard curve range: 7-5000 pg/mL
(Aβ1-42)
inter-assay cv: <10%
intra-assay cv: <5%
Technique(s)
multiplexing: suitable
Méthode de détection
fluorometric (Luminex xMAP)
Conditions d'expédition
ambient
Description générale
The MILLIPLEX® Mouse Amyloid Beta Bead Panel enables you to evaluate and quantitate Aβ40 and Aβ42 in your mouse research models. Coupled with the Luminex® xMAP® platform in a bead format, you receive the advantage of ideal speed and sensitivity, allowing quantitative multiplex detection of multiple analytes simultaneously, which can dramatically improve productivity.
The MILLIPLEX® Mouse Amyloid Beta Bead Panel is to be used for the simultaneous quantification of Aβ40 and Aβ42. This kit may be used only for the analysis mouse serum, plasma, cerebrospinal fluid (CSF) and tissue culture samples. This is a configurable assay, and one or both analytes can be selected: amyloid β40, amyloid β42. The MILLIPLEX® portfolio offers the broadest selection of analytes across a wide range of disease states and species. Once the analytes of interest have been identified, you can rely on the quality that we build into each kit to produce results you can trust. In addition to the assay characteristics listed in the protocol, other performance criteria evaluated during the validation process include: cross-reactivity, dilution linearity, kit stability and sample behavior (e.g. detectability and stability). Each panel and kit meets stringent manufacturing criteria to ensure batch-to-batch reproducibility.
Each MILLIPLEX® panel and kit includes:
Panel Type: Neuroscience
The MILLIPLEX® Mouse Amyloid Beta Bead Panel is to be used for the simultaneous quantification of Aβ40 and Aβ42. This kit may be used only for the analysis mouse serum, plasma, cerebrospinal fluid (CSF) and tissue culture samples. This is a configurable assay, and one or both analytes can be selected: amyloid β40, amyloid β42. The MILLIPLEX® portfolio offers the broadest selection of analytes across a wide range of disease states and species. Once the analytes of interest have been identified, you can rely on the quality that we build into each kit to produce results you can trust. In addition to the assay characteristics listed in the protocol, other performance criteria evaluated during the validation process include: cross-reactivity, dilution linearity, kit stability and sample behavior (e.g. detectability and stability). Each panel and kit meets stringent manufacturing criteria to ensure batch-to-batch reproducibility.
Each MILLIPLEX® panel and kit includes:
- Quality controls (QCs) provided to qualify assay performance
- Comparison of standard (calibrator) and QC lots to a reference lot to ensure lot-to-lot consistency
- Optimized serum matrix to mimic native analyte environment
- Detection antibody cocktails designed to yield consistent analyte profiles within panel MILLIPLEX® Mouse Amyloid Beta Bead Panel is part of the most versatile system available for your research. From our single to multiplex biomarker solutions, we partner with you to design, develop, analytically validate, and build the most comprehensive library available for protein detection and quantitation.
Panel Type: Neuroscience
Spécificité
Cross Reactivty
There was no or negligible cross-reactivity between the antibodies for an analyte and any of the other analytes within a panel.
There was no or negligible cross-reactivity between the antibodies for an analyte and any of the other analytes within a panel.
Application
- Analytes: Amyloid β40, Amyloid β42
- Recommended Sample type: serum, plasma, cerebrospinal fluid (CSF), and tissue culture
- Recommended Sample dilution: 1:2 dilution of serum or plasma, 1:10 dilution of cerebrospinal fluid (CSF), or neat/appropriately diluted tissue culture supernatant
- Assay Run Time:
- Research Category: Neuroscience Metabolism
- Research Subcategory: Category Metabolic Disorders Obesity Inflammation & Autoimmune Mechanisms
Caractéristiques et avantages
Design your multiplex kit by choosing available analytes within this panel.
Conditionnement
96-well plate
Everything you need in a single kit.
Composants
Mouse ABeta Standard, 1 vial, lyophilized
Mouse ABeta Quality Control 1, 1 vial, lyophilized
Mouse ABeta Quality Control 2, 1 vial, lyophilized
Serum Matrix (0.08% Sodium Azide) 1 vial, lyophilized
Set of one 96-Well Plate with 2 sealers
Assay Buffer, 1 bottle, 30 mL
Wash Buffer, 10X (0.05% Proclin), 1 bottle, 60 mL
Mouse ABeta Detection Antibody, 1 bottle, 3.2 mL
Streptavidin-Phycoerythrin, 1 bottle, 3.2 mL
Mixing Bottle, 1 bottle
Mouse ABeta Quality Control 1, 1 vial, lyophilized
Mouse ABeta Quality Control 2, 1 vial, lyophilized
Serum Matrix (0.08% Sodium Azide) 1 vial, lyophilized
Set of one 96-Well Plate with 2 sealers
Assay Buffer, 1 bottle, 30 mL
Wash Buffer, 10X (0.05% Proclin), 1 bottle, 60 mL
Mouse ABeta Detection Antibody, 1 bottle, 3.2 mL
Streptavidin-Phycoerythrin, 1 bottle, 3.2 mL
Mixing Bottle, 1 bottle
Stockage et stabilité
Recommended storage for kit components is 2 - 8°C.
Informations légales
Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp
Clause de non-responsabilité
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Mention d'avertissement
Danger
Mentions de danger
Classification des risques
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2
Organes cibles
Respiratory Tract
Code de la classe de stockage
10 - Combustible liquids
Certificats d'analyse (COA)
Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".
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Gayane Hrachia Buniatian et al.
Cells, 9(2) (2020-02-25)
The function and regulation of amyloid-beta (Aβ) in healthy and diseased liver remains unexplored. Because Aβ reduces the integrity of the blood-brain barrier we have examined its potential role in regulating the sinusoidal permeability of normal and cirrhotic liver. Aβ
Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..
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