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MAB1953

Sigma-Aldrich

Anti-Integrin αV Antibody, clone P3G8

clone P3G8, Chemicon®, from mouse

Synonyme(s) :

CD51

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About This Item

Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41

Source biologique

mouse

Niveau de qualité

Forme d'anticorps

purified antibody

Type de produit anticorps

primary antibodies

Clone

P3G8, monoclonal

Espèces réactives

human

Fabricant/nom de marque

Chemicon®

Technique(s)

ELISA: suitable
flow cytometry: suitable
immunocytochemistry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable

Isotype

IgG1

Numéro d'accès NCBI

Numéro d'accès UniProt

Conditions d'expédition

wet ice

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... ITGAV(3685)

Spécificité

Reacts with human alphaV integrin subunit and with all alphaV-containing integrin receptors.

Immunogène

UCLA P3 lung carcinoma cells

Application

Anti-Integrin αV Antibody, clone P3G8 is an antibody against Integrin αV for use in ELISA, FC, IP, IC, IH.
Immunohistochemistry: 1:1,000. For use on acetone or paraformaldehyde fixed tissue

Immunocytochemistry: 1:1,000. Will react with some lymphoid cell lines (B cells), many carcinoma and melanoma cell lines and osteosarcomas.

Flow cytometry

Immunoprecipitation

FACS

EIA

Optimal working dilutions must be determined by end user.
Research Category
Cell Structure
Research Sub Category
Integrins

Forme physique

Format: Purified

Stockage et stabilité

Maintain at 2-8°C in undiluted aliquots for up to 6 months.

Autres remarques

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Informations légales

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

Maria Rita Milone et al.
Oncotarget, 6(7), 5324-5341 (2014-12-08)
Proteomic analysis identified differentially expressed proteins between zoledronic acid-resistant and aggressive DU145R80 prostate cancer (PCa) cells and their parental DU145 cells. Ingenuity Pathway Analysis (IPA) showed a strong relationship between the identified proteins within a network associated with cancer and
Mannose 6-phosphate/insulin-like growth factor 2 receptor limits cell invasion by controlling alphaVbeta3 integrin expression and proteolytic processing of urokinase-type plasminogen activator receptor.
Schiller, HB; Szekeres, A; Binder, BR; Stockinger, H; Leksa, V
Molecular Biology of the Cell null
Keijiro Ishikawa et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 28(1), 131-142 (2013-09-12)
Proliferative vitreoretinopathy (PVR) is a severe, vision-threatening disorder characterized by the fibrous membrane formation that leads to tractional retinal detachment. There has been no effective therapeutic approach other than vitreoretinal surgery. In this study, DNA microarray analysis of the fibrous
Tropism-modified AAV vectors overcome barriers to successful cutaneous therapy.
Sallach, J; Di Pasquale, G; Larcher, F; Niehoff, N; Rubsam, M; Huber, A; Chiorini et al.
Molecular Therapy null
Tatyana I Gudz et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 26(9), 2458-2466 (2006-03-03)
In the mammalian CNS, oligodendrocyte precursor cells (OPCs) express most neurotransmitter receptors, but their function remains unclear. The current studies suggest a physiological role for glutamate (AMPA and/or kainate) receptors in OPC migration. AMPA stimulated alphav integrin-mediated OPC migration by

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