ABS448

Anti-CSN8 Antibody

from rabbit, purified by affinity chromatography

• Synonyme(s) : CSN8 Antibody, COP9 signalosome complex subunit 8, SGN8, JAB1-containing signalosome subunit 8, CSN8
• Code UNSPSC : 12352203
• eCl@ss : 32160702
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: rabbit
• Niveau de qualité: 100
• Forme d'anticorps: affinity isolated antibody
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Produit purifié par: affinity chromatography
• Espèces réactives: human
• Technique(s): western blot: suitable
• Numéro d'accès UniProt: Q99627
• Conditions d'expédition: wet ice
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... COPS8(10920)

Description

Description générale

COP9 signalosome complex subunit 8 (CSN8, COPS8), also known as Signalosome subunit 8 (SGN8), is a nuclear-enriched protein complex belonging to the CSN8 family. It is comprised of eight subunits that interact with deubiquitinating enzymes and protein kinases. The CSN complex is involved in the regulation of various signaling and developmental processes, including DNA repair, cell cycle regulation, embryogenesis, axonal guidance, MAPK cascade, immune response, and hormonal signaling.

Spécificité

This antibody recognizes the C-terminus of CSN8.

Immunogène

Epitope: C-terminus

KLH-conjugated linear peptide corresponding to the C-terminus of human CSN8.

Application

Anti-CSN8 Antibody is a highly specific rabbit polyclonal antibody, that targets COP9 signalosome complex subunit 8 & has been tested in western blotting.

Research Category
Signaling

Research Sub Category
Developmental Signaling

Qualité

Evaluated by Western Blotting in human liver tissue lysate.

Western Blotting Analysis: 2 µg/mL of this antibody detected CSN8 in 15 µg of human liver tissue lysate.

Description de la cible

~27 and ~30 kDa observed. Uniprot describes 2 isoforms at ~18 kDa and ~23 kDa Uncharacterized bands may appear in some lysate(s).

Liaison

Replaces: MABN1028

Forme physique

Antigen Affinity Purified

Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.

Stockage et stabilité

Stable for 1 year at 2-8°C from date of receipt.

Remarque sur l'analyse

Control
Human liver tissue lysate

Autres remarques

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable