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325317

Sigma-Aldrich

5-Bromo-2′,3′-dideoxyuridine

99%

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About This Item

Formule empirique (notation de Hill):
C9H11BrN2O4
Numéro CAS:
28616-93-5
Poids moléculaire :
291.10
Numéro MDL:
MFCD00013360

Essai

99%

Chaîne SMILES 

OC[C@@H]1CC[C@@H](O1)N2C=C(Br)C(=O)NC2=O

InChI

1S/C9H11BrN2O4/c10-6-3-12(9(15)11-8(6)14)7-2-1-5(4-13)16-7/h3,5,7,13H,1-2,4H2,(H,11,14,15)/t5-,7+/m0/s1

Clé InChI

MREZUWMZVPBIEE-CAHLUQPWSA-N

Application

Research tool for antiviral and anticancer studies.

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Makoto Hayashi et al.
The EMBO journal, 26(5), 1327-1339 (2007-02-17)
DNA replication of eukaryotic chromosomes initiates at a number of discrete loci, called replication origins. Distribution and regulation of origins are important for complete duplication of the genome. Here, we determined locations of Orc1 and Mcm6, components of pre-replicative complex
Ruben Guzman-Marin et al.
Sleep, 31(2), 167-175 (2008-02-16)
The dentate gyrus (DG) of the adult hippocampus contains progenitor cells, which have potential to differentiate into neurons. Previously we reported that 96 hours of total sleep deprivation reduces neurogenesis in the DG of adult rats. Loss of either non-rapid
H Kim et al.
Acta crystallographica. Section C, Crystal structure communications, 47 ( Pt 9), 1892-1895 (1991-09-15)
C9H11BrN2O4, Mr = 291.11, monoclinic, P2(1), a = 11.307 (1), b = 5.954 (1), c = 15.829 (2) A, beta = 93.25 (1) degree, V = 1063.90 A3, Z = 4, Dx = 1.82 g cm-3, lambda(Cu K alpha) =
Andrzej Wojcik et al.
Journal of photochemistry and photobiology. B, Biology, 69(2), 139-144 (2003-03-14)
The role of 5-bromo-2'-deoxyuridine (BrdU) in the formation of sister chromatid exchanges (SCEs) in cells exposed to UV radiation was studied. Cells were unifilarily labelled (labelling of one strand of chromosomal DNA) with BrdU or biotin-16-2'-deoxyuridine (biotin-dU) and irradiated in
Jean-Bernard Manent et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 25(19), 4755-4765 (2005-05-13)
Immature neurons express GABA and glutamate receptors before synapse formation, and both transmitters are released at an early developmental stage. We have now tested the hypothesis that the ongoing release of GABA and glutamate modulates neuronal migration. Using 5-bromo-2'-deoxyuridine labeling
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