VAV3
vav 3 guanine nucleotide exchange factor
- Human(10451) Summary: This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
- Mouse(57257) vav 3 oncogene
- Rat(295378) vav 3 guanine nucleotide exchange factor
- chicken(373939) vav 3 guanine nucleotide exchange factor
- domestic cat(101087417) vav 3 guanine nucleotide exchange factor
- Domestic Rabbit(100341627) vav 3 guanine nucleotide exchange factor
- dog(479921) vav 3 guanine nucleotide exchange factor
- domestic guinea pig(100714719) vav 3 guanine nucleotide exchange factor
- Horse(100057737) vav 3 guanine nucleotide exchange factor
- cow(521961) vav 3 guanine nucleotide exchange factor
- naked mole-rat(101716743) vav 3 guanine nucleotide exchange factor
- sheep(101120709) vav 3 guanine nucleotide exchange factor
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