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Merck

STAT1

signal transducer and activator of transcription 1, 91kDa

Synonymes:
CANDF7, ISGF-3, STAT91
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(6772) Summary: The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
  • Mouse(20846) signal transducer and activator of transcription 1
  • Rat(25124) signal transducer and activator of transcription 1
  • dog(488449) signal transducer and activator of transcription 1, 91kDa
  • sheep(100307049) signal transducer and activator of transcription 1, 91kDa
  • cow(510814) signal transducer and activator of transcription 1, 91kDa
  • Domestic Rabbit(100343893) signal transducer and activator of transcription 1, 91kDa
  • domestic guinea pig(100724708) signal transducer and activator of transcription 1, 91kDa
  • naked mole-rat(101718902) signal transducer and activator of transcription 1, 91kDa
  • chicken(424044) signal transducer and activator of transcription 1, 91kDa

Custom & Knockdown Gene Products

ELISA

Numéro du produit
Description
Espèce(s)
Phosphotyrosine STAT1 ELISA Kit, ,
Espèce(s)
human
Phospho-Stat1 (pTyr701) ELISA Kit, for detection of phospho-stat1 (pTyr701) and pan-stat1 in human or mouse cell and tissue lysates,
Espèce(s)
mouse, human
Phospho-Stat1 (pTyr701) and pan-Stat1 ELISA Kit, for detection of phospho-stat1 (pTyr701) and pan-stat1 in human or mouse cell and tissue lysates,
Espèce(s)
mouse, human
Phospho-Stat1 (pSer727) and pan-Stat1 ELISA Kit, for detection of phospho-stat1 (pSer727) and pan-stat1 in human or mouse cell and tissue lysates,
Espèce(s)
mouse, human
Cell-Based ELISA for detecting phospho-STAT1 (pTyr701) in cultured cell lines, 96 assays,
Espèce(s)
mouse, human

Antibodies

Numéro du produit
Description
Espèces réactives
Application
Anti-STAT1 antibody produced in rabbit, Ab2, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human, mouse, rat
Application
ChIP
immunofluorescence

immunohistochemistry

western blot
Anti-STAT1 antibody produced in rabbit, Ab1, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry

western blot
Anticorps anti-STAT1, CT, Upstate®, from rabbit,
Espèces réactives
human, mouse
Application
electrophoretic mobility shift assay
immunoprecipitation (IP)

western blot
Anti-phospho-STAT1 (pTyr701) antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse
Application
immunohistochemistry
western blot
Anti-STAT1 (isoform alpha) Antibody, clone 1D4 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Espèces réactives
human
Application
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot

Cell Lines

Numéro du produit
Description
Espèce(s)
A549 Cells GFP-STAT1, ,
Espèce(s)
human

Proteins

Numéro du produit
Description
Espèce(s)
STAT1 human, recombinant, expressed in insect cells, ≥70% (SDS-PAGE),
Espèce(s)
human
STAT1 β, GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Espèce(s)
human

esiRNA

Numéro du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human STAT1,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Stat1,
Espèce(s)
mouse