SNCA
synuclein, alpha (non A4 component of amyloid precursor)
Synonymes:
NACP, PARK1, PARK4, PD1
Espèce(s):
Human SNCA (6622), Mouse Snca (20617), Rat Snca (29219), cow SNCA (282857), naked mole-rat Snca (101700039), domestic cat SNCA (101091694), chicken SNCA (395393), sheep SNCA (100294604), dog SNCA (478478), Horse SNCA (100053270)
ID UniProtKB:
ID du gène:
- Human(6622) Summary: Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene. [provided by RefSeq, Mar 2009]
- Mouse(20617) synuclein, alpha
- Rat(29219) synuclein, alpha (non A4 component of amyloid precursor)
- cow(282857) synuclein, alpha (non A4 component of amyloid precursor)
- naked mole-rat(101700039) synuclein, alpha (non A4 component of amyloid precursor)
- domestic cat(101091694) synuclein, alpha (non A4 component of amyloid precursor)
- chicken(395393) synuclein, alpha (non A4 component of amyloid precursor)
- sheep(100294604) synuclein, alpha (non A4 component of amyloid precursor)
- dog(478478) synuclein, alpha (non A4 component of amyloid precursor)
- Horse(100053270) synuclein, alpha (non A4 component of amyloid precursor)
- domestic guinea pig(100725375) synuclein, alpha (non A4 component of amyloid precursor)
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Antibodies
Référence du produit
Description
Espèces réactives
Application
Anti-phospho-α-synuclein (Ser129) Antibody, clone PS129, ,
Espèces réactives
bovine, human, mouse, porcine, rat
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anticorps anti-α-synucléine agrégée, clone 5G4, clone 5G4, from mouse, purified by affinity chromatography,
Espèces réactives
human
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anticorps anti-phospho-α-synucléine (Ser129), clone 81A, clone 81A, from mouse,
Espèces réactives
human, mouse
Application
electron microscopy
immunocytochemistry
immunofluorescence
immunohistochemistry
western blot
immunocytochemistry
immunofluorescence
immunohistochemistry
western blot
Anti-α-Synuclein antibody, Mouse monoclonal, clone Syn211, purified from hybridoma cell culture,
Espèces réactives
human, zebra finch
Application
immunohistochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anticorps anti-a-synucléine, clone 10D2, clone 10D2, from mouse, purified by affinity chromatography,
Espèces réactives
human
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Proteins
Référence du produit
Description
Espèce(s)
α-Synuclein human, recombinant, expressed in E. coli, N-terminal histidine tagged, ≥90% (SDS-PAGE), lyophilized powder,
Espèce(s)
human
α-Synuclein A53T human, recombinant, expressed in E. coli, N-terminal histidine tagged, ≥90% (SDS-PAGE), lyophilized powder,
Espèce(s)
human
α-Synuclein E46K human, recombinant, expressed in E. coli, N-terminal histidine tagged, ≥90% (SDS-PAGE), lyophilized powder,
Espèce(s)
human