SLC7A11
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
Synonymes:
CCBR1, xCT
Espèce(s):
Human SLC7A11 (23657), Mouse Slc7a11 (26570), Rat Slc7a11 (310392), naked mole-rat Slc7a11 (101709765), domestic guinea pig Slc7a11 (100735308), domestic cat SLC7A11 (101099374), dog SLC7A11 (483821), chicken SLC7A11 (428731), sheep SLC7A11 (100820755), cow SLC7A11 (524078)
ID UniProtKB:
ID du gène:
- Human(23657) Summary: This gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc(-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also, increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels, resulting in neuronal cell death. [provided by RefSeq, Sep 2011]
- Mouse(26570) solute carrier family 7 (cationic amino acid transporter, y+ system), member 11
- Rat(310392) solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
- naked mole-rat(101709765) solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
- domestic guinea pig(100735308) solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
- domestic cat(101099374) solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
- dog(483821) solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
- chicken(428731) solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
- sheep(100820755) solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
- cow(524078) solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Numéro du produit
Description
Espèces réactives
Application
Anti-SLC7A11 antibody produced in rabbit, ,
Espèces réactives
mouse, rat
Application
western blot
Anti-SLC7A11/xCT antibody produced in rabbit, ,
Espèces réactives
human, mouse
Application
immunohistochemistry
western blot
western blot
Anti-SLC7A11 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Espèces réactives
human, rat
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-xCT Antibody, clone 3A12, ,
Espèces réactives
human
Application
immunocytochemistry
western blot
western blot
Anti-SLC7A11 antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human
Application
immunohistochemistry
esiRNA
Numéro du produit
Description
Espèce(s)