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Merck

SLC6A1

solute carrier family 6 (neurotransmitter transporter), member 1

Synonymes:
GABATHG, GABATR, GAT1
Espèce(s):
Human SLC6A1 (6529), Mouse Slc6a1 (232333), Rat Slc6a1 (79212), domestic guinea pig Slc6a1 (100731072), naked mole-rat Slc6a1 (101716075), sheep SLC6A1 (101121462), domestic cat SLC6A1 (101088066), Horse SLC6A1 (100051613), cow SLC6A1 (407118), chicken SLC6A1 (415960)
ID UniProtKB:
P30531, Q8N4K8
ID du gène:
  • Human(6529) Summary: The SLC6A1 gene encodes a gamma-aminobutyric acid (GABA) transporter, which removes GABA from the synaptic cleft (Hirunsatit et al., 2009 [PubMed 19077666]
  • Mouse(232333) solute carrier family 6 (neurotransmitter transporter, GABA), member 1
  • Rat(79212) solute carrier family 6 (neurotransmitter transporter), member 1
  • domestic guinea pig(100731072) solute carrier family 6 (neurotransmitter transporter, GABA), member 1
  • naked mole-rat(101716075) solute carrier family 6 (neurotransmitter transporter, GABA), member 1
  • sheep(101121462) solute carrier family 6 (neurotransmitter transporter, GABA), member 1
  • domestic cat(101088066) solute carrier family 6 (neurotransmitter transporter, GABA), member 1
  • Horse(100051613) solute carrier family 6 (neurotransmitter transporter, GABA), member 1
  • cow(407118) solute carrier family 6 (neurotransmitter transporter, GABA), member 1
  • chicken(415960) solute carrier family 6 (neurotransmitter transporter, GABA), member 1
  • dog(484655) solute carrier family 6 (neurotransmitter transporter, GABA), member 1

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Small Molecule - Antagonist

Référence du produit
Description
Espèce(s)
656364
(S)-(+)-3-Piperidinecarboxylic acid, 97%,
Espèce(s)
rat
P6273
2-Propylpentanoic acid, ,
Espèce(s)
rat, human, mouse
656356
(R)-(−)-3-Piperidinecarboxylic acid, 97%,
Espèce(s)
mouse, rat, human
A5835
γ-Aminobutyric acid, BioXtra, ≥99%,
Espèce(s)
rat, human
C8981
Carbamazepine, meets USP testing specifications,
Espèce(s)
rat, human

Antibodies

Référence du produit
Description
Espèces réactives
Application
AB1570
Anti-GABA Transporter-1 Antibody, CT (a.a. 588-599), Chemicon®, from rabbit,
Espèces réactives
feline, human, monkey, mouse, rabbit, rat
Application
immunohistochemistry
HPA013341
Anti-SLC6A1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human, mouse, rat
Application
immunohistochemistry
western blot
AB1570W
Anti-GABA Transporter-1 Antibody, Chemicon®, from rabbit,
Espèces réactives
feline, human, monkey, mouse, rabbit, rat
Application
immunohistochemistry
western blot
SAB2105532
Anti-SLC6A1 antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
bovine, dog, guinea pig, horse, human, mouse, rat
Application
western blot

Small Molecule - Inhibitor

Référence du produit
Description
Espèce(s)
SML0035
Tiagabine hydrochloride, ≥98% (HPLC),
Espèce(s)
human
T-081
Tiagabine hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
Espèce(s)
human
P6273
2-Propylpentanoic acid, ,
Espèce(s)
rat, human, mouse
D4007
5,5-Diphenylhydantoin, ≥98%,
Espèce(s)
human, rat
D4505
5,5-Diphenylhydantoin sodium salt, ≥99%,
Espèce(s)
human, rat

esiRNA

Référence du produit
Description
Espèce(s)
EHU153901
MISSION® esiRNA, targeting human SLC6A1,
Espèce(s)
human
EMU016731
MISSION® esiRNA, targeting mouse Slc6a1,
Espèce(s)
mouse