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Merck

SIGMAR1

sigma non-opioid intracellular receptor 1

Synonymes:
ALS16, OPRS1, SIG-1R, SR-BP, SR-BP1, SRBP, hSigmaR1, sigma1R
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(10280) Summary: This gene encodes a receptor protein that interacts with a variety of psychotomimetic drugs, including cocaine and amphetamines. The receptor is believed to play an important role in the cellular functions of various tissues associated with the endocrine, immune, and nervous systems. As indicated by its previous name, opioid receptor sigma 1 (OPRS1), the product of this gene was erroneously thought to function as an opioid receptor; it is now thought to be a non-opioid receptor. Alternative splicing of this gene results in transcript variants encoding distinct isoforms. [provided by RefSeq, Dec 2008]
  • Mouse(18391) sigma non-opioid intracellular receptor 1
  • Rat(29336) sigma non-opioid intracellular receptor 1
  • domestic guinea pig(100135589) sigma non-opioid intracellular receptor 1
  • cow(538903) sigma non-opioid intracellular receptor 1
  • sheep(101116710) sigma non-opioid intracellular receptor 1
  • domestic cat(101084912) sigma non-opioid intracellular receptor 1
  • Zebrafish(393952) sigma non-opioid intracellular receptor 1
  • chicken(100859748) sigma non-opioid intracellular receptor 1
  • dog(481587) sigma non-opioid intracellular receptor 1
  • naked mole-rat(101707150) sigma non-opioid intracellular receptor 1

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Small Molecule - Agonist

Référence du produit
Description
Espèce(s)
Dextromethorphan solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Espèce(s)
human
Dextromethorphan hydrobromide, United States Pharmacopeia (USP) Reference Standard,
Espèce(s)
human
Dextromethorphan HBr, certified reference material, pharmaceutical secondary standard,
Espèce(s)
human
Dextromethorphan hydrobromide, meets USP testing specifications,
Espèce(s)
human
Dextromethorphan hydrobromide, European Pharmacopoeia (EP) Reference Standard,
Espèce(s)
human

Small Molecule - Allosteric Modulator

Référence du produit
Description
Espèce(s)
Pentazocine solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Espèce(s)
human

Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-Sigma IR Antibody, clone ICR-SIG1R-A, clone ICR-SIG1R-A, from rat,
Espèces réactives
human, mouse
Application
flow cytometry
immunocytochemistry

immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-SIGMAR1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
ANTI-OPRS1 (CENTER) antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human, mouse
Application
western blot
ANTI-OPRS1(N-TERMINAL) antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
flow cytometry
western blot

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting mouse Sigmar1,
Espèce(s)
mouse