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Merck

SCNN1B

sodium channel, non-voltage-gated 1, beta subunit

Synonymes:
BESC1, ENaCb, ENaCbeta, SCNEB
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(6338) Summary: Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the beta subunit, and mutations in this gene have been associated with pseudohypoaldosteronism type 1 (PHA1), and Liddle syndrome. [provided by RefSeq, Apr 2009]
  • Mouse(20277) sodium channel, nonvoltage-gated 1 beta
  • Rat(24767) sodium channel, nonvoltage-gated 1, beta
  • chicken(427673) sodium channel, non-voltage-gated 1, beta subunit
  • dog(489972) sodium channel, non-voltage-gated 1, beta subunit
  • Horse(100069008) sodium channel, non-voltage-gated 1, beta subunit
  • domestic cat(101099767) sodium channel, non-voltage-gated 1, beta subunit
  • cow(533355) sodium channel, nonvoltage-gated 1, beta
  • sheep(100170325) sodium channel, non-voltage-gated 1, beta subunit
  • Goat(100861026) sodium channel, non-voltage-gated 1, beta subunit
  • Domestic Rabbit(100009564) sodium channel, non-voltage-gated 1, beta subunit
  • domestic guinea pig(100270805) sodium channel, nonvoltage-gated 1 beta
  • naked mole-rat(101717352) sodium channel, non-voltage-gated 1, beta subunit

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Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-SCNN1B antibody produced in rabbit, 1 mg/mL, affinity isolated antibody,
Espèces réactives
human, mouse, rat
Application
immunohistochemistry
immunoprecipitation (IP)

western blot
Anti-SCNN1B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
western blot
Monoclonal Anti-ENaC beta antibody produced in mouse, clone 7B8,
Espèces réactives
mouse
Application
immunohistochemistry
western blot
Monoclonal Anti-ENaC beta-Horseradish Peroxidase antibody produced in mouse, clone 16E4,
Espèces réactives
mouse
Application
western blot
Monoclonal Anti-ENaC beta-Horseradish Peroxidase antibody produced in mouse, clone 7B8,
Espèces réactives
mouse
Application
immunohistochemistry
western blot

Small Molecule - Blocker

Référence du produit
Description
Espèce(s)
Triamterene, ≥99%,
Espèce(s)
human
Triamterene, United States Pharmacopeia (USP) Reference Standard,
Espèce(s)
human
Triamterene, Pharmaceutical Secondary Standard; Certified Reference Material,
Espèce(s)
human
Triamterene, British Pharmacopoeia (BP) Reference Standard,
Espèce(s)
human
Triamterene, European Pharmacopoeia (EP) Reference Standard,
Espèce(s)
human

Small Molecule - Inhibitor

Référence du produit
Description
Espèce(s)
Benzamil hydrochloride hydrate, ≥98% (HPLC),
Espèce(s)
mouse, rat, human
Phenamil methanesulfonate salt, solid,
Espèce(s)
mouse, rat, human
5-(N-Methyl-N-isobutyl)­amiloride, ≥98% (TLC), powder,
Espèce(s)
mouse, rat, human
5-(N,N-Dimethyl)amiloride hydrochloride, ,
Espèce(s)
rat, mouse, human
5-(N,N-Hexamethylene)amiloride, ,
Espèce(s)
rat, human, mouse

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human SCNN1B,
Espèce(s)
human