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Merck

SARS2

seryl-tRNA synthetase 2, mitochondrial

Synonymes:
SARS, SARSM, SERS, SYS, SerRS, SerRSmt, mtSerRS
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(54938) Summary: This gene encodes the mitochondrial seryl-tRNA synthethase precursor, a member of the class II tRNA synthetase family. The mature enzyme catalyzes the ligation of Serine to tRNA(Ser) and participates in the biosynthesis of selenocysteinyl-tRNA(sec) in mitochondria. The enzyme contains an N-terminal tRNA binding domain and a core catalytic domain. It functions in a homodimeric form, which is stabilized by tRNA binding. This gene is regulated by a bidirectional promoter that also controls the expression of mitochondrial ribosomal protein S12. Both genes are within the critical interval for the autosomal dominant deafness locus DFNA4 and might be linked to this disease. Multiple transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Mar 2009]
  • Mouse(71984) seryl-aminoacyl-tRNA synthetase 2
  • Rat(292759) seryl-tRNA synthetase 2, mitochondrial
  • domestic cat(101093227) seryl-tRNA synthetase 2, mitochondrial
  • Zebrafish(394154) seryl-tRNA synthetase 2, mitochondrial
  • chicken(100858214) seryl-tRNA synthetase 2, mitochondrial
  • naked mole-rat(101718394) seryl-tRNA synthetase 2, mitochondrial
  • domestic guinea pig(100730340) seryl-tRNA synthetase 2, mitochondrial
  • sheep(101113878) seryl-tRNA synthetase 2, mitochondrial
  • dog(484518) seryl-tRNA synthetase 2, mitochondrial
  • cow(282060) seryl-tRNA synthetase 2, mitochondrial

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Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-SARS2 antibody produced in mouse, IgG fraction of antiserum, buffered aqueous solution,
Espèces réactives
human
Application
western blot
Anti-SARS2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
western blot
Anti-SARS2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
Anti-SARS2 (N-term) antibody produced in rabbit, saturated ammonium sulfate (SAS) precipitated, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
immunohistochemistry

western blot
Anti-SARS2 (26-40) antibody produced in rabbit, IgG fraction of antiserum,
Espèces réactives
human
Application
western blot

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human SARS2,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Sars2,
Espèce(s)
mouse