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Merck

PTPRE

protein tyrosine phosphatase, receptor type, E

Synonymes:
HPTPE, PTPE, R-PTP-EPSILON
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(5791) Summary: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Two alternatively spliced transcript variants of this gene have been reported, one of which encodes a receptor-type PTP that possesses a short extracellular domain, a single transmembrane region, and two tandem intracytoplasmic catalytic domains; Another one encodes a PTP that contains a distinct hydrophilic N-terminus, and thus represents a nonreceptor-type isoform of this PTP. Studies of the similar gene in mice suggested the regulatory roles of this PTP in RAS related signal transduction pathways, cytokines induced SATA signaling, as well as the activation of voltage-gated K+ channels. [provided by RefSeq, Jul 2008]
  • Mouse(19267) protein tyrosine phosphatase, receptor type, E
  • Rat(114767) protein tyrosine phosphatase, receptor type, E
  • chicken(423962) protein tyrosine phosphatase, receptor type, E
  • domestic cat(101082346) protein tyrosine phosphatase, receptor type, E
  • Horse(100049870) protein tyrosine phosphatase, receptor type, E
  • dog(609852) protein tyrosine phosphatase, receptor type, E
  • sheep(101117715) protein tyrosine phosphatase, receptor type, E
  • cow(505285) protein tyrosine phosphatase, receptor type, E
  • naked mole-rat(101716090) protein tyrosine phosphatase, receptor type, E
  • domestic guinea pig(100731255) protein tyrosine phosphatase, receptor type, E

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Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-PTPRE antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry
Anti-PTPRE antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
Monoclonal Anti-PTPRE antibody produced in mouse, clone 2D10, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
immunofluorescence

Proteins

Référence du produit
Description
Espèce(s)
PTPRE, active, GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Espèce(s)
human

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human PTPRE,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Ptpre,
Espèce(s)
mouse