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Merck

PRKCD

protein kinase C, delta

Synonymes:
MAY1, PKCD, nPKC-delta
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(5580) Summary: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. Studies both in human and mice demonstrate that this kinase is involved in B cell signaling and in the regulation of growth, apoptosis, and differentiation of a variety of cell types. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008]
  • Mouse(18753) protein kinase C, delta
  • Rat(170538) protein kinase C, delta
  • domestic cat(101087716) protein kinase C, delta
  • chicken(415905) protein kinase C, delta
  • domestic guinea pig(100726624) protein kinase C, delta
  • naked mole-rat(101718422) protein kinase C, delta
  • sheep(101107639) protein kinase C, delta
  • Domestic Rabbit(100008966) protein kinase C, delta
  • cow(505708) protein kinase C, delta
  • sheep(100294651) protein kinase C, delta
  • dog(494005) protein kinase C, delta

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Small Molecule - Agonist

Référence du produit
Description
Espèce(s)
Acide oléique, ≥99% (GC),
Espèce(s)
human

Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-PRKCD antibody produced in rabbit, Ab2, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry

western blot
Anti-PRKCD antibody produced in rabbit, Ab1, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry

western blot
Anti-phospho-PKCδ (Ser664) Antibody, Upstate®, from rabbit,
Espèces réactives
human
Application
western blot
Anti-PKC δ antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse, rat
Application
ELISA
immunohistochemistry

western blot
Anti-Protein Kinase Cδ antibody produced in rabbit, whole antiserum,
Espèces réactives
rat
Application
dot blot
microarray

western blot

Small Molecule - Inhibitor

Référence du produit
Description
Espèce(s)
Phorbol 12,13-dibutyrate, ≥98% (TLC), powder,
Espèce(s)
mouse
H-7 dihydrochloride, ≥98% (HPLC),
Espèce(s)
human
Tamoxifen citrate salt, ≥99%,
Espèce(s)
human
Acide oléique, ≥99% (GC),
Espèce(s)
human
UCN-01, ≥97% (HPLC), powder,
Espèce(s)
human

Proteins

Référence du produit
Description
Espèce(s)
PKCδ Protein, active, 10 µg, Active, N-terminal His6-tagged, recombinant amino acids 2-end, of human PKCδ. For use in Kinase Assays.,
Espèce(s)
human
PKC-δ, active, GST tagged human, PRECISIO®, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Espèce(s)
human
Protein Kinase Cδ isozyme human, >95% (SDS-PAGE), recombinant, expressed in baculovirus infected insect cells, buffered aqueous glycerol solution,
Espèce(s)
human

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human PRKCD,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Prkcd,
Espèce(s)
mouse