PRKCB
protein kinase C, beta
Synonymes:
PKC-beta, PKCB, PRKCB1, PRKCB2
Espèce(s):
Human PRKCB (5579), Mouse Prkcb (18751), Rat Prkcb (25023), Domestic Rabbit PRKCB (100037719), sheep PRKCB (101118410), naked mole-rat Prkcb (101722702), domestic cat PRKCB (101088970), chicken PRKCB (416567), dog PRKCB (489968), cow PRKCB (282325)
ID UniProtKB:
ID du gène:
- Human(5579) Summary: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption. Studies in mice also suggest that this kinase may also regulate neuronal functions and correlate fear-induced conflict behavior after stress. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
- Mouse(18751) protein kinase C, beta
- Rat(25023) protein kinase C, beta
- Domestic Rabbit(100037719) protein kinase C, beta
- sheep(101118410) protein kinase C, beta
- naked mole-rat(101722702) protein kinase C, beta
- domestic cat(101088970) protein kinase C, beta
- chicken(416567) protein kinase C, beta
- dog(489968) protein kinase C, beta
- cow(282325) protein kinase C, beta
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Small Molecule - Agonist
Numéro du produit
Description
Espèce(s)
Antibodies
Numéro du produit
Description
Espèces réactives
Application
Anti-PRKCB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-p-PKCβ (Ser660) Antibody, clone 2C11 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Espèces réactives
bovine, human, monkey, mouse, rabbit, rat
Application
affinity binding assay
immunocytochemistry
inhibition assay
western blot
immunocytochemistry
inhibition assay
western blot
Anti-PKCβ Antibody, clone 2E13 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Espèces réactives
human, monkey, mouse
Application
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Anti-PRKCB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Espèces réactives
human
Application
immunofluorescence
Anti-Phospho-PKCalpha/beta II-T638/641 antibody produced in rabbit, ,
Espèces réactives
human
Application
western blot
Small Molecule - Inhibitor
Proteins
Numéro du produit
Description
Espèce(s)
Protein kinase CβII isozyme human, >85% (SDS-PAGE), recombinant, expressed in baculovirus infected insect cells, buffered aqueous glycerol solution,
Espèce(s)
human