PRKCA
protein kinase C, alpha
Synonymes:
AAG6, PKC-alpha, PKCA, PRKACA
Espèce(s):
Human PRKCA (5578), Mouse Prkca (18750), Rat Prkca (24680), Horse PRKCA (100063318), dog PRKCA (490904), Domestic Rabbit PRKCA (100037720), domestic cat PRKCA (101086433), sheep PRKCA (101110074), Zebrafish prkca (497384), chicken PRKCA (417430) ...Plus
ID UniProtKB:
ID du gène:
- Human(5578) Summary: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes. [provided by RefSeq, Jul 2008]
- Mouse(18750) protein kinase C, alpha
- Rat(24680) protein kinase C, alpha
- Horse(100063318) protein kinase C, alpha
- dog(490904) protein kinase C, alpha
- Domestic Rabbit(100037720) protein kinase C, alpha
- domestic cat(101086433) protein kinase C, alpha
- sheep(101110074) protein kinase C, alpha
- Zebrafish(497384) protein kinase C, alpha
- chicken(417430) protein kinase C, alpha
- cow(282001) protein kinase C, alpha
- domestic guinea pig(100302324) protein kinase C, alpha
- domestic guinea pig(100713627) protein kinase C, alpha
- naked mole-rat(101716044) protein kinase C, alpha
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Small Molecule - Activator
Numéro du produit
Description
Espèce(s)
Small Molecule - Agonist
Numéro du produit
Description
Espèce(s)
Antibodies
Numéro du produit
Description
Espèces réactives
Application
Anti-PKC Antibody (α, β, γ), clone M110, clone M110, Upstate®, from mouse,
Espèces réactives
human, mouse, rat
Application
ELISA
immunocytochemistry
immunoprecipitation (IP)
western blot
immunocytochemistry
immunoprecipitation (IP)
western blot
Anti-phospho-PKCα (Ser657/Tyr658) Antibody, Upstate®, from rabbit,
Espèces réactives
human, rabbit, rat
Application
ELISA
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-Phospho-PKCalpha-S226 antibody produced in rabbit, ,
Espèces réactives
human, mouse, rat
Application
western blot
Anti-Phospho-PKC (pan) (βII Ser660) antibody produced in rabbit, ,
Espèces réactives
human, mouse, rat
Application
western blot
Anti-PKC α antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse, rat
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Small Molecule - Inhibitor
Numéro du produit
Description
Espèce(s)
Proteins
Numéro du produit
Description
Espèce(s)
Protein kinase Cα isozyme human, ≥70% (SDS-PAGE), recombinant, expressed in baculovirus infected insect cells, buffered aqueous glycerol solution,
Espèce(s)
human
PKCα Protein, active, 10 µg, Active, recombinant, full-length human PKCα, containing N-terminal His6 tag. For use in Kinase Assays.,
Espèce(s)
human
PKC-α, active, GST tagged from Xanopus sp., PRECISIO®, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Espèce(s)