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Merck

PRDM16

PR domain containing 16

Synonymes:
CMD1LL, LVNC8, MEL1, PFM13
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(63976) Summary: The reciprocal translocation t(1;3)(p36;q21) occurs in a subset of myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). This gene is located near the 1p36.3 breakpoint and has been shown to be specifically expressed in the t(1:3)(p36,q21)-positive MDS/AML. The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal PR domain. The translocation results in the overexpression of a truncated version of this protein that lacks the PR domain, which may play an important role in the pathogenesis of MDS and AML. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
  • Mouse(70673) PR domain containing 16
  • Rat(100366024) PR domain containing 16
  • dog(479582) PR domain containing 16
  • domestic cat(101090880) PR domain containing 16
  • sheep(101120004) PR domain containing 16
  • cow(100137803) PR domain containing 16
  • Horse(100060844) PR domain containing 16
  • Zebrafish(559174) PR domain containing 16
  • domestic guinea pig(100714489) PR domain containing 16
  • naked mole-rat(101721685) PR domain containing 16
  • chicken(419388) PR domain containing 16

Custom & Knockdown Gene Products

Antibodies

Numéro du produit
Description
Espèces réactives
Application
Anticorps anti-PRDM16, from rabbit, purified by affinity chromatography,
Espèces réactives
human, rat
Application
immunofluorescence
immunohistochemistry

western blot
Anti-PRDM16 Antibody, from rabbit, purified by affinity chromatography,
Espèces réactives
bovine, canine, guinea pig, horse, human, nonhuman primates
Application
immunohistochemistry
immunoprecipitation (IP)

western blot
Anti-PRDM16 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Espèces réactives
human
Application
immunofluorescence
Anti-PRDM16 antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse
Application
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-PRDM16 (N-term) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
immunohistochemistry