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Merck

PPP1R1B

protein phosphatase 1, regulatory (inhibitor) subunit 1B

Synonymes:
DARPP-32, DARPP32
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(84152) Summary: This gene encodes a bifunctional signal transduction molecule. Dopaminergic and glutamatergic receptor stimulation regulates its phosphorylation and function as a kinase or phosphatase inhibitor. As a target for dopamine, this gene may serve as a therapeutic target for neurologic and psychiatric disorders. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
  • Mouse(19049) protein phosphatase 1, regulatory (inhibitor) subunit 1B
  • Rat(360616) protein phosphatase 1, regulatory (inhibitor) subunit 1B
  • cow(282459) protein phosphatase 1, regulatory (inhibitor) subunit 1B
  • domestic cat(101090972) protein phosphatase 1, regulatory (inhibitor) subunit 1B
  • dog(608394) protein phosphatase 1, regulatory (inhibitor) subunit 1B
  • sheep(101103077) protein phosphatase 1, regulatory (inhibitor) subunit 1B
  • Zebrafish(100884132) protein phosphatase 1, regulatory (inhibitor) subunit 1B
  • chicken(426639) protein phosphatase 1, regulatory (inhibitor) subunit 1B
  • naked mole-rat(101708486) protein phosphatase 1, regulatory (inhibitor) subunit 1B
  • domestic guinea pig(100726824) protein phosphatase 1, regulatory (inhibitor) subunit 1B

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Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-DARPP-32 Antibody, from rabbit, purified by affinity chromatography,
Espèces réactives
canine, mouse, rat, rhesus macaque, rhesus monkey
Application
immunoprecipitation (IP)
western blot
Anti-DARPP-32 Antibody, clone 9B6.1, clone 9B6.1, from mouse,
Espèces réactives
human, rat
Application
immunohistochemistry
western blot
Anti-DARPP-32 Antibody, phosphoThr34, Chemicon®, from rabbit,
Espèces réactives
human, mouse, rat
Application
western blot
Anti-DARPP-32 antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse, rat
Application
ELISA
immunohistochemistry

western blot
Anti-PPP1R1B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human, mouse
Application
immunohistochemistry
western blot

Proteins

Référence du produit
Description
Espèce(s)
DARPP-32, recombinant, His-tagged, ,
Espèce(s)
human

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human PPP1R1B,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Ppp1r1b,
Espèce(s)
mouse