PPARA
peroxisome proliferator-activated receptor alpha
Synonymes:
NR1C1, PPAR, PPARalpha, hPPAR
Espèce(s):
Human PPARA (5465), Mouse Ppara (19013), Rat Ppara (25747), domestic guinea pig Ppara (100135604), chicken PPARA (374120), naked mole-rat Ppara (101725514), Domestic Rabbit PPARA (100009308), Goat PPARA (100861393), sheep PPARA (100190976), dog PPARA (403654) ...Plus
ID UniProtKB:
ID du gène:
- Human(5465) Summary: Peroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers; this term arises because they induce an increase in the size and number of peroxisomes. Peroxisomes are subcellular organelles found in plants and animals that contain enzymes for respiration and for cholesterol and lipid metabolism. The action of peroxisome proliferators is thought to be mediated via specific receptors, called PPARs, which belong to the steroid hormone receptor superfamily. PPARs affect the expression of target genes involved in cell proliferation, cell differentiation and in immune and inflammation responses. Three closely related subtypes (alpha, beta/delta, and gamma) have been identified. This gene encodes the subtype PPAR-alpha, which is a nuclear transcription factor. Multiple alternatively spliced transcript variants have been described for this gene, although the full-length nature of only two has been determined. [provided by RefSeq, Jul 2008]
- Mouse(19013) peroxisome proliferator activated receptor alpha
- Rat(25747) peroxisome proliferator activated receptor alpha
- domestic guinea pig(100135604) peroxisome proliferator activated receptor alpha
- chicken(374120) peroxisome proliferator-activated receptor alpha
- naked mole-rat(101725514) peroxisome proliferator-activated receptor alpha
- Domestic Rabbit(100009308) peroxisome proliferator-activated receptor alpha
- Goat(100861393) peroxisome proliferator-activated receptor alpha
- sheep(100190976) peroxisome proliferator-activated receptor alpha
- dog(403654) peroxisome proliferator-activated receptor alpha
- Horse(100049840) peroxisome proliferator-activated receptor alpha
- domestic cat(101095837) peroxisome proliferator-activated receptor alpha
- domestic cat(100049013) peroxisome proliferator-activated receptor alpha
- cow(281992) peroxisome proliferator-activated receptor alpha
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Small Molecule - Activator
Small Molecule - Agonist
Numéro du produit
Description
Espèce(s)
Fenofibrate Related Compound B, United States Pharmacopeia (USP) Reference Standard,
Espèce(s)
human
Small Molecule - Antagonist
Antibodies
Numéro du produit
Description
Espèces réactives
Application
Anti-PPAR-α antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse, rat
Application
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Anti-PPAR α Antibody, ascites fluid, Chemicon®,
Espèces réactives
human, mouse
Application
ELISA
immunocytochemistry
western blot
immunocytochemistry
western blot
Anti-PPARα Antibody, clone 4G22 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Espèces réactives
bovine, canine, feline, human, monkey, mouse, porcine, rat
Application
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Anti-phospho PPAR alpha (Ser73), from rabbit,
Espèces réactives
bovine, human, mouse, rat
Application
dot blot
immunocytochemistry
immunofluorescence
immunohistochemistry
western blot
immunocytochemistry
immunofluorescence
immunohistochemistry
western blot
Anti-PPARA antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, rat
Application
western blot
Proteins
Numéro du produit
Description
Espèce(s)
PPARα, ligand binding domain (170-468) human, recombinant, expressed in E. coli, ≥80% (SDS-PAGE),
Espèce(s)
human
PPARα isotype, GST tagged human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE),
Espèce(s)
human
PPARα isotype, ligand binding domain, GST tagged human, recombinant, expressed in E. coli, ≥80% (SDS-PAGE),
Espèce(s)
human
esiRNA
Numéro du produit
Description
Espèce(s)