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Merck

POT1

protection of telomeres 1

Synonymes:
HPOT1
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(25913) Summary: This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008]
  • Rat(500054) protection of telomeres 1
  • chicken(404538) protection of telomeres 1 homolog (S. pombe)
  • Zebrafish(566847) protection of telomeres 1 homolog
  • domestic guinea pig(100725051) protection of telomeres 1
  • naked mole-rat(101698900) protection of telomeres 1
  • sheep(101107695) protection of telomeres 1 homolog (S. pombe)
  • cow(511292) protection of telomeres 1
  • Horse(100071610) protection of telomeres 1 homolog (S. pombe)
  • domestic cat(101097225) protection of telomeres 1 homolog (S. pombe)
  • dog(609119) protection of telomeres 1 homolog (S. pombe)

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Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-POT1 Antibody, clone 43B7, ,
Espèces réactives
human
Application
immunoprecipitation (IP)
western blot
Anti-POT1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Espèces réactives
human
Application
immunofluorescence
Anti-POT1, affinity isolated antibody,
Espèces réactives
human
Application
immunohistochemistry

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human POT1,
Espèce(s)
human