Accéder au contenu
Merck

PLOD1

procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1

Synonymes:
EDS6, LH, LH1, LLH, PLOD
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(5351) Summary: Lysyl hydroxylase is a membrane-bound homodimeric protein localized to the cisternae of the endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VI have deficiencies in lysyl hydroxylase activity. [provided by RefSeq, Jul 2008]
  • Mouse(18822) procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
  • Rat(116552) procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
  • domestic guinea pig(100714306) procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
  • domestic cat(101100822) procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
  • sheep(101111306) procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
  • cow(281409) procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
  • Goat(100861039) procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
  • dog(487440) procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
  • naked mole-rat(101716463) procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
  • chicken(419485) procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Référence du produit
Description
Espèces réactives
Application
ANTI-PLOD1 (N-TERM) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Espèces réactives
human
Application
immunohistochemistry
western blot
Anti-PLOD1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
western blot
Anti-PLOD1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
western blot

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human PLOD1,
Espèce(s)
human