PLCG1
phospholipase C, gamma 1
Synonymes:
NCKAP3, PLC-II, PLC1, PLC148, PLCgamma1
Espèce(s):
Human PLCG1 (5335), Mouse Plcg1 (18803), Rat Plcg1 (25738), naked mole-rat Plcg1 (101705192), chicken PLCG1 (419175), dog PLCG1 (485874), Zebrafish plcg1 (373867), domestic cat PLCG1 (101092925), cow PLCG1 (281987), domestic guinea pig Plcg1 (100716986)
ID UniProtKB:
ID du gène:
- Human(5335) Summary: The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(18803) phospholipase C, gamma 1
- Rat(25738) phospholipase C, gamma 1
- naked mole-rat(101705192) phospholipase C, gamma 1
- chicken(419175) phospholipase C, gamma 1
- dog(485874) phospholipase C, gamma 1
- Zebrafish(373867) phospholipase C, gamma 1
- domestic cat(101092925) phospholipase C, gamma 1
- cow(281987) phospholipase C, gamma 1
- domestic guinea pig(100716986) phospholipase C, gamma 1
- sheep(101103341) phospholipase C, gamma 1
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Antibodies
Numéro du produit
Description
Espèces réactives
Application
Anti-PLCγ-1 Antibody, Upstate®, from mouse,
Espèces réactives
bovine, human, mouse, rabbit, rat
Application
immunocytochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-Phospho-PLC gamma 1 (PLCG1)-Y783 antibody produced in rabbit, ,
Espèces réactives
human, mouse, rat
Application
western blot
Anti-PLCG1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-PLCγ-1 Antibody, clone B-6-4, clone B-6-4, 1 mg/mL, Upstate®,
Espèces réactives
bovine, human, mouse, rabbit, rat
Application
immunoprecipitation (IP)
western blot
western blot
Monoclonal Anti-PLCG1 antibody produced in mouse, clone 2A2, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
immunofluorescence
proximity ligation assay
western blot
immunofluorescence
proximity ligation assay
western blot