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Merck

PIK3CB

phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta

Synonymes:
P110BETA, PI3K, PI3KBETA, PIK3C1
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(5291) Summary: This gene encodes an isoform of the catalytic subunit of phosphoinositide 3-kinase (PI3K). These kinases are important in signaling pathways involving receptors on the outer membrane of eukaryotic cells and are named for their catalytic subunit. The encoded protein is the catalytic subunit for PI3Kbeta (PI3KB). PI3KB has been shown to be part of the activation pathway in neutrophils which have bound immune complexes at sites of injury or infection. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2011]
  • Mouse(74769) phosphatidylinositol 3-kinase, catalytic, beta polypeptide
  • Rat(85243) phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
  • dog(477085) phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
  • naked mole-rat(101715249) phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
  • domestic cat(101091892) phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
  • sheep(101109759) phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
  • cow(517948) phosphoinositide-3-kinase, catalytic, beta polypeptide
  • Zebrafish(100002263) phosphoinositide-3-kinase, catalytic, beta polypeptide
  • chicken(424826) phosphoinositide-3-kinase, catalytic, beta polypeptide
  • Horse(100051753) phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
  • Domestic Rabbit(100345181) phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
  • domestic guinea pig(100727986) phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta

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Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-PI3 Kinase Antibody, p110β, from rabbit, purified by affinity chromatography,
Espèces réactives
canine, dog, human, monkey, mouse, rat
Application
ELISA
immunocytochemistry

immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-PI3 Kinase p110 β Antibody, clone 1D18 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Espèces réactives
human, monkey, porcine
Application
affinity binding assay
immunohistochemistry

western blot
Anti-PIK3CB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Espèces réactives
human
Application
immunofluorescence
western blot
Monoclonal Anti-PIK3CB antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL9518, purified immunoglobulin, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry
Monoclonal Anti-PIK3CB antibody produced in mouse, clone 10D5, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
immunofluorescence

proximity ligation assay

western blot

Small Molecule - Inhibitor

Référence du produit
Description
Espèce(s)
PF-04691502, ≥98% (HPLC),
Espèce(s)
human

Proteins

Référence du produit
Description
Espèce(s)
PI3K (p110-β/p85-β), active, His tagged human, PRECISIO®, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Espèce(s)
human

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human PIK3CB,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Pik3cb,
Espèce(s)
mouse