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Merck

MMP8

matrix metallopeptidase 8 (neutrophil collagenase)

Synonymes:
CLG1, HNC, MMP-8, PMNL-CL
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(4317) Summary: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is stored in secondary granules within neutrophils and is activated by autolytic cleavage. Its function is degradation of type I, II and III collagens. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008]
  • Mouse(17394) matrix metallopeptidase 8
  • Rat(63849) matrix metallopeptidase 8
  • domestic guinea pig(100724670) matrix metallopeptidase 8 (neutrophil collagenase)
  • naked mole-rat(101716969) matrix metallopeptidase 8 (neutrophil collagenase)
  • sheep(101120601) matrix metallopeptidase 8 (neutrophil collagenase)
  • domestic cat(101080995) matrix metallopeptidase 8 (neutrophil collagenase)
  • Horse(100069005) matrix metallopeptidase 8 (neutrophil collagenase)
  • cow(100336575) matrix metallopeptidase 8 (neutrophil collagenase)
  • dog(489429) matrix metallopeptidase 8 (neutrophil collagenase)

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ELISA

Référence du produit
Description
Espèce(s)
Human MMP-8 ELISA Kit, for serum, plasma, conditioned medium, urine,
Espèce(s)
human
Rat MMP-8 ELISA Kit, for serum, plasma, cell culture supernatant,
Espèce(s)
mouse

Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-MMP8 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab2,
Espèces réactives
human
Application
immunohistochemistry
Anti-MMP8 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab1,
Espèces réactives
human
Application
immunohistochemistry
Anti-Mmp8 Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence

Small Molecule - Inhibitor

Référence du produit
Description
Espèce(s)
Doxycycline monohydrate, ,
Espèce(s)
human
Doxycycline Monohydrate, United States Pharmacopeia (USP) Reference Standard,
Espèce(s)
human
α-Sexithiophene, ,
Espèce(s)
human, rat
Marimastat, ≥98% (HPLC),
Espèce(s)
human, rat, mouse
CP-101537, ≥98% (HPLC),
Espèce(s)
human, rat, mouse

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human MMP8,
Espèce(s)
human