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Merck

MAPK9

mitogen-activated protein kinase 9

Synonymes:
JNK-55, JNK2, JNK2A, JNK2ALPHA, JNK2B, JNK2BETA, PRKM9, SAPK, SAPK1a, p54a, p54aSAPK
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(5601) Summary: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase targets specific transcription factors, and thus mediates immediate-early gene expression in response to various cell stimuli. It is most closely related to MAPK8, both of which are involved in UV radiation induced apoptosis, thought to be related to the cytochrome c-mediated cell death pathway. This gene and MAPK8 are also known as c-Jun N-terminal kinases. This kinase blocks the ubiquitination of tumor suppressor p53, and thus it increases the stability of p53 in nonstressed cells. Studies of this gene's mouse counterpart suggest a key role in T-cell differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Sep 2008]
  • Mouse(26420) mitogen-activated protein kinase 9
  • Rat(50658) mitogen-activated protein kinase 9
  • Zebrafish(100149273) mitogen-activated protein kinase 9
  • chicken(395983) mitogen-activated protein kinase 9
  • cow(534125) mitogen-activated protein kinase 9
  • domestic cat(101084765) mitogen-activated protein kinase 9
  • Horse(100057961) mitogen-activated protein kinase 9
  • dog(474652) mitogen-activated protein kinase 9
  • Domestic Rabbit(100342664) mitogen-activated protein kinase 9
  • sheep(101120826) mitogen-activated protein kinase 9
  • domestic guinea pig(100714249) mitogen-activated protein kinase 9
  • naked mole-rat(101698286) mitogen-activated protein kinase 9

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Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-JNK2 Antibody, clone 1F16 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Espèces réactives
bovine, canine, human, mouse
Application
immunocytochemistry
immunohistochemistry

western blot
Anti-phospho-MAPK9 (pThr183) antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse, rat
Application
immunohistochemistry
western blot
Monoclonal Anti-MAPK9 antibody produced in mouse, clone 1C1-3A8, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
immunohistochemistry

western blot
ANTI-MAPK9 antibody produced in mouse, clone 3C12, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
immunofluorescence

western blot
Anti-MAPK9 antibody produced in rabbit, ,
Espèces réactives
human, mouse
Application
immunofluorescence
immunohistochemistry

western blot

Small Molecule - Inhibitor

Référence du produit
Description
Espèce(s)
SP600125, ≥98% (HPLC),
Espèce(s)
human
Adénine, ≥99%,
Espèce(s)
human, rat, mouse
Adénine, BioReagent, suitable for cell culture,
Espèce(s)
human, rat, mouse
Adénine, BioReagent, suitable for plant cell culture, ≥99%,
Espèce(s)
human, rat, mouse
α-Sexithiophene, ,
Espèce(s)
human, rat

Proteins

Référence du produit
Description
Espèce(s)
JNK2α2/SAPK1a Protein, active, 10 µg, Active, N-terminal His-tagged, full length human JNK2α2/SAPK1a, for use in Kinase Assays.,
Espèce(s)
human
JNK2, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Espèce(s)
human
JNK2α2/SAPK1a Protein, inactive, 50 g, Unactive, N-terminal His6-tagged, recombinant, full-length, human JNK2α2/SAPK1a unactive, for use in Kinase Assays.,
Espèce(s)
human

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human MAPK9,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Mapk9,
Espèce(s)
mouse