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Merck

LIN28B

lin-28 homolog B (C. elegans)

Synonymes:
CSDD2
Espèce(s):
Human LIN28B (389421), Mouse Lin28b (380669), Rat Lin28b (689054), chicken LIN28B (421786), sheep LIN28B (100861578), cow LIN28B (540646), domestic cat LIN28B (101090940), dog LIN28B (481943), domestic guinea pig Lin28b (100734141)
ID UniProtKB:
Q6ZN17, A1L165, B2RPN6, Q5TCM4
ID du gène:
  • Human(389421) Summary: The protein encoded by this gene belongs to the lin-28 family, which is characterized by the presence of a cold-shock domain and a pair of CCHC zinc finger domains. This gene is highly expressed in testis, fetal liver, placenta, and in primary human tumors and cancer cell lines. It is negatively regulated by microRNAs that target sites in the 3' UTR, and overexpression of this gene in primary tumors is linked to the repression of let-7 family of microRNAs and derepression of let-7 targets, which facilitates cellular transformation. [provided by RefSeq, Jun 2012]
  • Mouse(380669) lin-28 homolog B (C. elegans)
  • Rat(689054) lin-28 homolog B (C. elegans)
  • chicken(421786) lin-28 homolog B (C. elegans)
  • sheep(100861578) lin-28 homolog B (C. elegans)
  • cow(540646) lin-28 homolog B (C. elegans)
  • domestic cat(101090940) lin-28 homolog B (C. elegans)
  • dog(481943) lin-28 homolog B (C. elegans)
  • domestic guinea pig(100734141) lin-28 homolog B (C. elegans)

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Antibodies

Référence du produit
Description
Espèces réactives
Application
ZRB2199
Anti-LIN28B Antibody, clone 1H17 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Espèces réactives
human, monkey
Application
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
HPA061745
Anti-LIN28B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry
western blot
HPA036630
Anti-LIN28B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
MABE885
Anti-Lin-28B, clone 15G3 Antibody, clone 15G3, from mouse,
Espèces réactives
human
Application
immunocytochemistry
immunoprecipitation (IP)
western blot
MABE884
Anti-Lin-28B, clone 17A2 Antibody, clone 17A2, from mouse,
Espèces réactives
human
Application
immunocytochemistry
immunoprecipitation (IP)
western blot

esiRNA

Référence du produit
Description
Espèce(s)
EMU204151
MISSION® esiRNA, targeting mouse Lin28b,
Espèce(s)
mouse
EHU050781
MISSION® esiRNA, targeting human LIN28B,
Espèce(s)
human