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Merck

KCNMA1

potassium large conductance calcium-activated channel, subfamily M, alpha member 1

Synonymes:
BKTM, KCa1.1, MaxiK, SAKCA, SLO, SLO-ALPHA, SLO1, bA205K10.1, mSLO1
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(3778) Summary: MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit, which is the product of this gene, and the modulatory beta subunit. Intracellular calcium regulates the physical association between the alpha and beta subunits. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
  • Mouse(16531) potassium large conductance calcium-activated channel, subfamily M, alpha member 1
  • Rat(83731) potassium large conductance calcium-activated channel, subfamily M, alpha member 1
  • domestic cat(101099080) potassium large conductance calcium-activated channel, subfamily M, alpha member 1
  • cow(282573) potassium large conductance calcium-activated channel, subfamily M, alpha member 1
  • sheep(100270685) potassium large conductance calcium-activated channel, subfamily M, alpha member 1
  • chicken(374065) potassium large conductance calcium-activated channel, subfamily M, alpha member 1
  • naked mole-rat(101726007) potassium large conductance calcium-activated channel, subfamily M, alpha member 1
  • dog(403984) potassium large conductance calcium-activated channel, subfamily M, alpha member 1
  • domestic guinea pig(100728344) potassium large conductance calcium-activated channel, subfamily M, alpha member 1

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Small Molecule - Agonist

Référence du produit
Description
Espèce(s)
NS 1619, powder,
Espèce(s)
mouse, rat
Diazoxide, ,
Espèce(s)
rat, mouse, human

Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-Slo1 Antibody, clone L6/60, clone L6/60, from mouse,
Espèces réactives
mouse, rat
Application
immunocytochemistry
immunohistochemistry

western blot
Anti-Maxi K/BK channel Antibody, clone 3D15 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Espèces réactives
bovine, feline, horse, human, monkey, mouse, rat, sheep
Application
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot
Anti-KCNMA1 antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat, sheep
Application
immunohistochemistry
western blot
Anti-KCNMA1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
Anti-KCNMA1 antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
xenopus, bovine, chicken, hamster, horse, human, monkey, mouse, pig, rabbit, rat, zebrafish
Application
immunohistochemistry

Small Molecule - Opener

Référence du produit
Description
Espèce(s)
BMS 204352, ≥98% (HPLC),
Espèce(s)
human
Diazoxide, ,
Espèce(s)
rat, mouse, human

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting mouse Kcnma1,
Espèce(s)
mouse
MISSION® esiRNA, targeting human KCNMA1,
Espèce(s)
human