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Merck

KCNJ8

potassium inwardly-rectifying channel, subfamily J, member 8

Synonymes:
KIR6.1, uKATP-1
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(3764) Summary: Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins. Defects in this gene may be a cause of J-wave syndromes and sudden infant death syndrome (SIDS). [provided by RefSeq, May 2012]
  • Mouse(16523) potassium inwardly-rectifying channel, subfamily J, member 8
  • Rat(25472) potassium inwardly-rectifying channel, subfamily J, member 8
  • dog(486639) potassium inwardly-rectifying channel, subfamily J, member 8
  • chicken(395973) potassium inwardly-rectifying channel, subfamily J, member 8
  • Zebrafish(561090) potassium inwardly-rectifying channel, subfamily J, member 8
  • sheep(101118008) potassium inwardly-rectifying channel, subfamily J, member 8
  • cow(282572) potassium inwardly-rectifying channel, subfamily J, member 8
  • domestic cat(101092773) potassium inwardly-rectifying channel, subfamily J, member 8
  • Horse(100064325) potassium inwardly-rectifying channel, subfamily J, member 8
  • naked mole-rat(101698456) potassium inwardly-rectifying channel, subfamily J, member 8
  • domestic guinea pig(100379255) potassium inwardly-rectifying channel, subfamily J, member 8

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Small Molecule - Activator

Référence du produit
Description
Espèce(s)
Diazoxide, ,
Espèce(s)
rat, mouse, human

Small Molecule - Agonist

Référence du produit
Description
Espèce(s)
Cromakalim, ,
Espèce(s)
rat
Diazoxide, ,
Espèce(s)
rat, mouse, human

Antibodies

Référence du produit
Description
Espèces réactives
Application
Monoclonal Anti-Kir6.1 antibody produced in mouse, clone S366-60,
Espèces réactives
human, rat
Application
immunofluorescence
western blot
Anti-KCNJ8 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
western blot
Monoclonal Anti-Kir6.1-Atto 594 antibody produced in mouse, clone S366-60,
Espèces réactives
human, rat
Application
immunofluorescence
western blot
Monoclonal Anti-Kir6.1-Allophycocyanin antibody produced in mouse, clone S366-60,
Espèces réactives
human, rat
Application
immunofluorescence
western blot
Monoclonal Anti-Kir6.1-FITC antibody produced in mouse, clone S366-60,
Espèces réactives
human, rat
Application
immunofluorescence
western blot

Small Molecule - Opener

Référence du produit
Description
Espèce(s)
Diazoxide, United States Pharmacopeia (USP) Reference Standard,
Espèce(s)
human
Diazoxide, European Pharmacopoeia (EP) Reference Standard,
Espèce(s)
human
Diazoxide, ,
Espèce(s)
rat, mouse, human

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human KCNJ8,
Espèce(s)
human