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Merck

IKBKG

inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma

Synonymes:
AMCBX1, FIP-3, FIP3, Fip3p, IKK-gamma, IP, IP1, IP2, IPD2, NEMO, ZC2HC9
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(8517) Summary: This gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex, which activates NF-kappaB resulting in activation of genes involved in inflammation, immunity, cell survival, and other pathways. Mutations in this gene result in incontinentia pigmenti, hypohidrotic ectodermal dysplasia, and several other types of immunodeficiencies. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome. [provided by RefSeq, Aug 2011]
  • Mouse(16151) inhibitor of kappaB kinase gamma
  • Rat(309295) inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
  • Domestic Rabbit(100328905) inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
  • domestic guinea pig(100722308) inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
  • naked mole-rat(101712077) inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
  • dog(612576) inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
  • domestic cat(101086544) inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
  • cow(281855) inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
  • Zebrafish(541530) inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
  • sheep(101107332) inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma

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Small Molecule - Antagonist

Référence du produit
Description
Espèce(s)
Parthenolide, ≥98% (HPLC),
Espèce(s)
human

Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-IKBKG antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human, mouse, rat
Application
immunofluorescence
immunohistochemistry

western blot
Anti-IKK-γ antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human
Application
ELISA
immunohistochemistry

western blot
Anti-IKKγ antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Espèces réactives
human, mouse, rat
Application
ELISA
immunocytochemistry

western blot
Anti-IKKγ Antibody, Upstate®, from mouse,
Espèces réactives
human, mouse
Application
western blot
Anti-Phospho-IKKγ-S376 antibody produced in rabbit, ,
Espèces réactives
human, mouse
Application
immunohistochemistry
western blot

Proteins

Référence du produit
Description
Espèce(s)
IKK-γ, GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Espèce(s)
human

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human IKBKG,
Espèce(s)
human