HIF1A
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
Synonymes:
HIF-1A, HIF-1alpha, HIF1, HIF1-ALPHA, MOP1, PASD8, bHLHe78
Espèce(s):
Human HIF1A (3091), Mouse Hif1a (15251), Rat Hif1a (29560), dog HIF1A (480348), domestic guinea pig Hif1a (100713113), naked mole-rat Hif1a (101715845), Domestic Rabbit HIF1A (100009579), sheep HIF1A (443519), cow HIF1A (281814), domestic cat HIF1A (101083686)
ID UniProtKB:
ID du gène:
- Human(3091) Summary: This gene encodes the alpha subunit of transcription factor hypoxia-inducible factor-1 (HIF-1), which is a heterodimer composed of an alpha and a beta subunit. HIF-1 functions as a master regulator of cellular and systemic homeostatic response to hypoxia by activating transcription of many genes, including those involved in energy metabolism, angiogenesis, apoptosis, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. HIF-1 thus plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2011]
- Mouse(15251) hypoxia inducible factor 1, alpha subunit
- Rat(29560) hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
- dog(480348) hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
- domestic guinea pig(100713113) hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
- naked mole-rat(101715845) hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
- Domestic Rabbit(100009579) hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
- sheep(443519) hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
- cow(281814) hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
- domestic cat(101083686) hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
- chicken(374177) hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
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ELISA
Référence du produit
Description
Espèce(s)
Human HIF-1 alpha ELISA Kit, for cell culture supernatants, plasma, and serum samples,
Espèce(s)
human
Antibodies
Référence du produit
Description
Espèces réactives
Application
Anti-HIF-1α Antibody, clone 2B14 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Espèces réactives
human, monkey
Application
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Anti-HIF1A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
Anti-Hypoxia Inducible Factor 1 α Antibody, clone H1α67, clone H1alpha67, Chemicon®, from mouse,
Espèces réactives
ferret, human, mouse, rat
Application
electrophoretic mobility shift assay
immunohistochemistry
immunoprecipitation (IP)
western blot
immunohistochemistry
immunoprecipitation (IP)
western blot
Anti-HIF1A antibody produced in rabbit, ,
Espèces réactives
bovine, human, mouse, rat
Application
ChIP
immunocytochemistry
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot
immunocytochemistry
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot
Anti-HIF-1 alpha antibody, Rabbit monoclonal, recombinant, expressed in HEK 293 cells, clone RM242, purified immunoglobulin,
Espèces réactives
human
Application
immunohistochemistry
western blot
western blot