HEXA
hexosaminidase A (alpha polypeptide)
Synonymes:
TSD
Espèce(s):
Human HEXA (3073), Mouse Hexa (15211), Rat Hexa (300757), chicken HEXA (415320), Zebrafish hexa (323613), domestic guinea pig Hexa (100712955), naked mole-rat Hexa (101718368), domestic cat HEXA (101091627), dog HEXA (487633), Horse HEXA (100063584) ...Plus
ID UniProtKB:
ID du gène:
- Human(3073) Summary: This gene encodes the alpha subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Alpha subunit gene mutations lead to Tay-Sachs disease (GM2-gangliosidosis type I). [provided by RefSeq, Jul 2009]
- Mouse(15211) hexosaminidase A
- Rat(300757) hexosaminidase A
- chicken(415320) hexosaminidase A (alpha polypeptide)
- Zebrafish(323613) hexosaminidase A (alpha polypeptide)
- domestic guinea pig(100712955) hexosaminidase A (alpha polypeptide)
- naked mole-rat(101718368) hexosaminidase A (alpha polypeptide)
- domestic cat(101091627) hexosaminidase A (alpha polypeptide)
- dog(487633) hexosaminidase A (alpha polypeptide)
- Horse(100063584) hexosaminidase A (alpha polypeptide)
- sheep(100145856) hexosaminidase A (alpha polypeptide)
- cow(504468) hexosaminidase A (alpha polypeptide)
- Domestic Rabbit(100008950) hexosaminidase A (alpha polypeptide)
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ELISA
Numéro du produit
Description
Espèce(s)
Antibodies
Numéro du produit
Description
Espèces réactives
Application
Anti-HEXA (C-terminal) antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
bovine, canine, guinea pig, horse, human, mouse, pig, rabbit, sheep
Application
immunohistochemistry
western blot
western blot
Anti-HEXA antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
Anti-HEXA antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
western blot
Small Molecule - Inhibitor
esiRNA
Numéro du produit
Description
Espèce(s)