Accéder au contenu
Merck

GUCA2B

guanylate cyclase activator 2B (uroguanylin)

Synonymes:
GCAP-II, UGN
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(2981) Summary: This gene encodes a member of the guanylin family, and is expressed in the stomach and intestine. This protein functions as an endogenous ligand for the guanylate cyclase-C receptor and stimulates an increase in cyclic GMP, a key component of several intracellular signal transduction pathways. It maybe involved in salt and water secretion into the intestinal lumen as well as the renal tubules, and thus regulate electrolyte homeostasis in these tissues. [provided by RefSeq, Oct 2011]
  • Mouse(14916) guanylate cyclase activator 2b (retina)
  • Rat(64055) guanylate cyclase activator 2B
  • dog(100684829) guanylate cyclase activator 2B (uroguanylin)
  • naked mole-rat(101720311) guanylate cyclase activator 2B (uroguanylin)
  • domestic guinea pig(100135535) guanylate cyclase activator 2b (retina)
  • domestic cat(101092381) guanylate cyclase activator 2B (uroguanylin)
  • Zebrafish(325935) guanylate cyclase activator 2B (uroguanylin)
  • cow(515664) guanylate cyclase activator 2B (uroguanylin)

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Small Molecule - Antagonist

Référence du produit
Description
Espèce(s)
Acide kynurénique, ≥98%,
Espèce(s)
rat, human

Antibodies

Référence du produit
Description
Espèces réactives
Application
ANTI-GUCA2B (C-TERM) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Espèces réactives
human
Application
western blot

Proteins

Référence du produit
Description
Espèce(s)
Uroguanylin, ≥90% (HPLC),
Espèce(s)
human

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human GUCA2B,
Espèce(s)
human