GRPR
gastrin-releasing peptide receptor
Synonymes:
Espèce(s):
Human GRPR (2925), Mouse Grpr (14829), Rat Grpr (24938), Zebrafish grpr (567289), naked mole-rat Grpr (101701702), cow GRPR (532784), chicken GRPR (378928), domestic cat GRPR (101096951), dog GRPR (491754), domestic guinea pig Grpr (100734491) ...Plus
ID UniProtKB:
ID du gène:
- Human(2925) Summary: Gastrin-releasing peptide (GRP) regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation and is a potent mitogen for neoplastic tissues. The effects of GRP are mediated through the gastrin-releasing peptide receptor. This receptor is a glycosylated, 7-transmembrane G-protein coupled receptor that activates the phospholipase C signaling pathway. The receptor is aberrantly expressed in numerous cancers such as those of the lung, colon, and prostate. An individual with autism and multiple exostoses was found to have a balanced translocation between chromosome 8 and a chromosome X breakpoint located within the gastrin-releasing peptide receptor gene. [provided by RefSeq, Jul 2008]
- Mouse(14829) gastrin releasing peptide receptor
- Rat(24938) gastrin releasing peptide receptor
- Zebrafish(567289) gastrin-releasing peptide receptor
- naked mole-rat(101701702) gastrin-releasing peptide receptor
- cow(532784) gastrin-releasing peptide receptor
- chicken(378928) gastrin-releasing peptide receptor
- domestic cat(101096951) gastrin-releasing peptide receptor
- dog(491754) gastrin-releasing peptide receptor
- domestic guinea pig(100734491) gastrin-releasing peptide receptor
- Horse(100056400) gastrin-releasing peptide receptor
- sheep(100142675) gastrin-releasing peptide receptor
- Domestic Rabbit(100344857) gastrin-releasing peptide receptor
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Small Molecule - Antagonist
Référence du produit
Description
Espèce(s)
Antibodies
Référence du produit
Description
Espèces réactives
Application
ANTI-GRPR (CENTER) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Espèces réactives
human
Application
flow cytometry
immunohistochemistry
western blot
immunohistochemistry
western blot