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Merck

GRIK2

glutamate receptor, ionotropic, kainate 2

Synonymes:
EAA4, GLR6, GLUK6, GLUR6, GluK2, MRT6
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(2898) Summary: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing at multiple sites within the first and second transmembrane domains, which is thought to alter the structure and function of the receptor complex. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. Mutations in this gene have been associated with autosomal recessive mental retardation. [provided by RefSeq, Jul 2008]
  • Mouse(14806) glutamate receptor, ionotropic, kainate 2 (beta 2)
  • Rat(54257) glutamate receptor, ionotropic, kainate 2
  • chicken(428628) glutamate receptor, ionotropic, kainate 2
  • dog(481938) glutamate receptor, ionotropic, kainate 2
  • Thale Cress(836176) geminivirus rep interacting kinase 2
  • Zebrafish(556013) glutamate receptor, ionotropic, kainate 2
  • cow(615226) glutamate receptor, ionotropic, kainate 2
  • naked mole-rat(101697577) glutamate receptor, ionotropic, kainate 2
  • domestic guinea pig(100733104) glutamate receptor, ionotropic, kainate 2
  • sheep(101122701) glutamate receptor, ionotropic, kainate 2

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Small Molecule - Agonist

Référence du produit
Description
Espèce(s)
L-Glutamic acid hydrochloride, ,
Espèce(s)
human
(±)-AMPA, solid,
Espèce(s)
rat
(S)-AMPA, ≥97%,
Espèce(s)
mouse, human, rat
Kainic acid monohydrate, ≥99% (TLC),
Espèce(s)
human, mouse, rat
Acide (Aminométhyl)phosphonique, 99%,
Espèce(s)
rat, human

Small Molecule - Antagonist

Référence du produit
Description
Espèce(s)
CNQX, ≥98% (HPLC), solid,
Espèce(s)
rat
NBQX disodium salt hydrate, ≥98% (HPLC),
Espèce(s)
human
DNQX, ≥98% (TLC),
Espèce(s)
mouse, rat, human
(±)-AMPA, solid,
Espèce(s)
rat
(S)-AMPA, ≥97%,
Espèce(s)
mouse, human, rat

Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-GluR6/7 Antibody, clone NL9, rabbit monoclonal, culture supernatant, clone NL904, Upstate®,
Espèces réactives
human, mouse, rat
Application
immunoprecipitation (IP)
western blot
Anti-GRIK2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human, mouse, rat
Application
immunohistochemistry
western blot
Anti-GRIK2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
Anti-GRIK2 antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Application
western blot
Anti-GRIK2 (AB2) antibody produced in rabbit, IgG fraction of antiserum,
Espèces réactives
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Application
immunohistochemistry
western blot

Small Molecule - Mixed Agonist/Antagonist

Référence du produit
Description
Espèce(s)
(±)-AMPA, solid,
Espèce(s)
rat
Kainic acid monohydrate, ≥99% (TLC),
Espèce(s)
human, mouse, rat
L-Glutamic acid, ReagentPlus®, ≥99% (HPLC),
Espèce(s)
rat, human
L-Glutamic acid, from non-animal source, meets EP testing specifications, suitable for cell culture, 98.5-100.5%,
Espèce(s)
rat, human
L-Glutamic acid, BioUltra, ≥99.5% (NT),
Espèce(s)
rat, human

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human GRIK2 (1),
Espèce(s)
human
MISSION® esiRNA, targeting human GRIK2 (2),
Espèce(s)
human