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Merck

GLUD1

glutamate dehydrogenase 1

Synonymes:
GDH, GDH1, GLUD
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(2746) Summary: This gene encodes glutamate dehydrogenase protein; a mitochondrial matrix enzyme that catalyzes the oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. This enzyme has an important role in regulating amino acid induced insulin secretion and activating mutations in this gene are a common cause of congenital hyperinsulinism. This enzyme is allosterically activated by ADP and inhibited by GTP and ATP. The related glutamate dehydrogenase 2 gene on the human X-chromosome originated from this gene via retrotransposition and encodes a soluble form of glutamate dehydrogenase. Multiple pseudogenes of this gene are present in humans.[provided by RefSeq, Sep 2009]
  • Mouse(14661) glutamate dehydrogenase 1
  • Rat(24399) glutamate dehydrogenase 1
  • naked mole-rat(101699446) glutamate dehydrogenase 1
  • domestic guinea pig(100722523) glutamate dehydrogenase 1
  • sheep(443239) glutamate dehydrogenase 1
  • cow(281785) glutamate dehydrogenase 1
  • dog(100684847) glutamate dehydrogenase 1
  • chicken(423612) glutamate dehydrogenase 1

Custom & Knockdown Gene Products

Antibodies

Numéro du produit
Description
Espèces réactives
Application
Anti-GLUD1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Espèces réactives
human
Application
immunofluorescence
western blot
Anti-GLUD1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
Anti-GLUD1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry

western blot
Anti-GLUD1 antibody produced in rabbit, ,
Espèces réactives
human, mouse, rat
Application
immunohistochemistry
western blot
Anti-GLUD1, affinity isolated antibody,
Espèces réactives
bovine, dog, horse, human, mouse, pig, rabbit, rat, sheep
Application
immunohistochemistry
western blot

Proteins

Numéro du produit
Description
Espèce(s)
Glutamate Dehydrogenase (GlDH), from beef liver,
Espèce(s)
cow
L-Glutamic Dehydrogenase from bovine liver, Type III, lyophilized powder, ≥20 units/mg protein,
Espèce(s)
cow
L-Glutamic Dehydrogenase from bovine liver, Type I, ammonium sulfate suspension, ≥40 units/mg protein,
Espèce(s)
cow

esiRNA

Numéro du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human GLUD1,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Glud1,
Espèce(s)
mouse