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Merck

GABRG2

gamma-aminobutyric acid (GABA) A receptor, gamma 2

Synonymes:
CAE2, ECA2, GEFSP3
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(2566) Summary: This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammlian brain, where it acts at GABA-A receptors, which are ligand-gated chloride channels. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene have been associated with epilepsy and febrile seizures. Multiple transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(14406) gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2
  • Rat(29709) gamma-aminobutyric acid (GABA) A receptor, gamma 2
  • Horse(100059571) gamma-aminobutyric acid (GABA) A receptor, gamma 2
  • sheep(101118526) gamma-aminobutyric acid (GABA) A receptor, gamma 2
  • Zebrafish(553402) gamma-aminobutyric acid (GABA) A receptor, gamma 2
  • chicken(396289) gamma-aminobutyric acid (GABA) A receptor, gamma 2
  • dog(489141) gamma-aminobutyric acid (GABA) A receptor, gamma 2
  • domestic cat(100286791) gamma-aminobutyric acid (GABA) A receptor, gamma 2
  • cow(282240) gamma-aminobutyric acid (GABA) A receptor, gamma 2
  • domestic guinea pig(100723005) gamma-aminobutyric acid (GABA) A receptor, gamma 2
  • naked mole-rat(101718598) gamma-aminobutyric acid (GABA) A receptor, gamma 2

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Small Molecule - Agonist

Référence du produit
Description
Espèce(s)
Meprobamate solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Espèce(s)
human
γ-Aminobutyric acid, ≥99%,
Espèce(s)
human, rat
2-Bromo-2-chloro-1,1,1-trifluoroethane, ≥99%,
Espèce(s)
human

Small Molecule - Allosteric Modulator

Référence du produit
Description
Espèce(s)
Zolpidem solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Espèce(s)
human
Zaleplon solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Espèce(s)
human
Midazolam solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Espèce(s)
human
Diazepam solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Espèce(s)
human
Oxazepam solution, 1 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Espèce(s)
human

Small Molecule - Antagonist

Référence du produit
Description
Espèce(s)
Etiocholan-3α-ol-17-one, ,
Espèce(s)
human, rat
Flumazenil, United States Pharmacopeia (USP) Reference Standard,
Espèce(s)
human
Ganaxolone, ≥98% (HPLC), solid,
Espèce(s)
human, mouse
2,6-Diisopropylphenol, 97%,
Espèce(s)
human
Flumazenil, >99% (HPLC), solid,
Espèce(s)
rat, human

Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-GABA A Receptor γ2 Antibody, cytoplasmic loop, Chemicon®, from rabbit,
Espèces réactives
rat
Application
immunoprecipitation (IP)
western blot
Anti-GABA(A) receptor subunit gamma-2 Antibody, serum, from rabbit,
Espèces réactives
human, rat
Application
western blot
Anti-GABA(A) receptor subunit gamma-2 Antibody, clone 10F10-C1-B8, clone 10F10-C1-B8, from mouse,
Espèces réactives
rat
Application
immunocytochemistry
western blot
Anti-GABRG2 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Espèces réactives
bovine, human, mouse, rat
Application
ELISA
western blot
Anti-GABAA Receptor (γ2 subunit) (extracellular) antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
Espèces réactives
bovine, human, mouse, rat
Application
western blot

Small Molecule - Mixed Agonist/Antagonist

Référence du produit
Description
Espèce(s)
Etiocholan-3α-ol-17-one, ,
Espèce(s)
human, rat
Ganaxolone, ≥98% (HPLC), solid,
Espèce(s)
human, mouse
5α-Pregnan-3α-ol-20-one, solid,
Espèce(s)
human, mouse, rat

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human GABRG2,
Espèce(s)
human