GABRA4
gamma-aminobutyric acid (GABA) A receptor, alpha 4
Synonymes:
Espèce(s):
Human GABRA4 (2557), Mouse Gabra4 (14397), Rat Gabra4 (140675), chicken GABRA4 (422770), cow GABRA4 (282238), dog GABRA4 (482132), sheep GABRA4 (101121776), domestic cat GABRA4 (101098052), domestic guinea pig Gabra4 (100721252), naked mole-rat Gabra4 (101718327)
ID UniProtKB:
ID du gène:
- Human(2557) Summary: Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. This gene encodes subunit alpha-4, which is involved in the etiology of autism and eventually increases autism risk through interaction with another subunit, gamma-aminobutyric acid receptor beta-1 (GABRB1). Alternatively spliced transcript variants encoding different isoforms have been found in this gene.[provided by RefSeq, Feb 2011]
- Mouse(14397) gamma-aminobutyric acid (GABA) A receptor, subunit alpha 4
- Rat(140675) gamma-aminobutyric acid (GABA) A receptor, alpha 4
- chicken(422770) gamma-aminobutyric acid (GABA) A receptor, alpha 4
- cow(282238) gamma-aminobutyric acid (GABA) A receptor, alpha 4
- dog(482132) gamma-aminobutyric acid (GABA) A receptor, alpha 4
- sheep(101121776) gamma-aminobutyric acid (GABA) A receptor, alpha 4
- domestic cat(101098052) gamma-aminobutyric acid (GABA) A receptor, alpha 4
- domestic guinea pig(100721252) gamma-aminobutyric acid (GABA) A receptor, alpha 4
- naked mole-rat(101718327) gamma-aminobutyric acid (GABA) A receptor, alpha 4
- Domestic Rabbit(100339882) gamma-aminobutyric acid (GABA) A receptor, alpha 4
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Small Molecule - Agonist
Référence du produit
Description
Espèce(s)
Meprobamate solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Espèce(s)
human
Small Molecule - Allosteric Modulator
Référence du produit
Description
Espèce(s)
Midazolam solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Espèce(s)
human
Diazepam solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Espèce(s)
human
Small Molecule - Antagonist
Référence du produit
Description
Espèce(s)
Antibodies
Référence du produit
Description
Espèces réactives
Application
α, Chemicon®, from rabbit,
Espèces réactives
human, mouse, rat
Application
immunoprecipitation (IP)
western blot
western blot
Anti-GABRA4 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Espèces réactives
bovine, human
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Monoclonal Anti-GABA A Receptor-Atto 390 antibody produced in mouse, clone S398A-34,
Espèces réactives
human, mouse
Application
immunofluorescence
western blot
western blot
Monoclonal Anti-GABA A Receptor-Horseradish Peroxidase antibody produced in mouse, clone S398A-34,
Espèces réactives
human, mouse
Application
immunofluorescence
western blot
western blot
Monoclonal Anti-GABA A Receptor-R-Phycoerythrin antibody produced in mouse, clone S398A-34,
Espèces réactives
human, mouse
Application
immunofluorescence
western blot
western blot
Small Molecule - Inhibitor
Référence du produit
Description
Espèce(s)