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Merck

FGFR1OP

FGFR1 oncogene partner

Synonymes:
FOP
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(11116) Summary: This gene encodes a largely hydrophilic centrosomal protein that is required for anchoring microtubules to subcellular structures. A t(6;8)(q27;p11) chromosomal translocation, fusing this gene and the fibroblast growth factor receptor 1 (FGFR1) gene, has been found in cases of myeloproliferative disorder. The resulting chimeric protein contains the N-terminal leucine-rich region of this encoded protein fused to the catalytic domain of FGFR1. Alterations in this gene may also be associated with Crohn's disease, Graves' disease, and vitiligo. Alternatively spliced transcript variants that encode different proteins have been identified. [provided by RefSeq, Jul 2013]
  • Mouse(75296) Fgfr1 oncogene partner
  • Rat(365103) FGFR1 oncogene partner
  • sheep(101115039) FGFR1 oncogene partner
  • domestic cat(101099885) FGFR1 oncogene partner
  • dog(612453) FGFR1 oncogene partner
  • Zebrafish(415215) FGFR1 oncogene partner
  • chicken(421568) FGFR1 oncogene partner
  • domestic guinea pig(100728960) FGFR1 oncogene partner
  • cow(506246) FGFR1 oncogene partner
  • naked mole-rat(101707272) FGFR1 oncogene partner

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Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-FGFR1OP antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Espèces réactives
human
Application
immunofluorescence
Anti-FGFR1 antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse, rat
Application
ELISA
immunohistochemistry

western blot
Monoclonal Anti-FGFR1OP antibody produced in mouse, clone 1E8, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
western blot
Anti-FGFR1OP antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
immunofluorescence
western blot

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human FGFR1OP,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Fgfr1op,
Espèce(s)
mouse