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Merck

F3

coagulation factor III (thromboplastin, tissue factor)

Synonymes:
CD142, TF, TFA
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(2152) Summary: This gene encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
  • Mouse(14066) coagulation factor III
  • Rat(25584) coagulation factor III (thromboplastin, tissue factor)
  • naked mole-rat(101702267) coagulation factor III (thromboplastin, tissue factor)
  • domestic guinea pig(100135463) coagulation factor III
  • Domestic Rabbit(100009127) coagulation factor III (thromboplastin, tissue factor)
  • sheep(101118918) coagulation factor III (thromboplastin, tissue factor)
  • cow(280686) coagulation factor III
  • domestic cat(101082330) coagulation factor III (thromboplastin, tissue factor)
  • dog(490153) coagulation factor III (thromboplastin, tissue factor)
  • chicken(429084) coagulation factor III (thromboplastin, tissue factor)

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ELISA

Référence du produit
Description
Espèce(s)
Human F3 / Tissue Factor ELISA Kit, ,
Espèce(s)
human
MouseCoagulation Factor III ELISA Kit, for cell culture supernatants, plasma, and serum samples,
Espèce(s)
mouse

Antibodies

Référence du produit
Description
Espèces réactives
Application
Monoclonal Anti-CD142 PE produced in mouse, ,
Espèces réactives
human
Application
flow cytometry
Anti-Tissue Factor Antibody, clone 2L10 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Espèces réactives
human
Application
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot
Anti-Tissue Factor/CD142 Antibody, clone HTF-1, ,
Espèces réactives
bovine, human
Application
ELISA
dot blot

flow cytometry

immunohistochemistry

inhibition assay

western blot
Monoclonal Anti-CD142 antibody produced in mouse, clone HTF-1,
Espèces réactives
human
Application
flow cytometry
Anti-F3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Espèces réactives
human
Application
immunofluorescence
western blot

Proteins

Référence du produit
Description
Espèce(s)
Thromboplastin from rabbit, ,
Espèce(s)
domestic rabbit

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human F3,
Espèce(s)
human