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Merck

DACT1

dishevelled-binding antagonist of beta-catenin 1

Synonymes:
DAPPER, DAPPER1, DPR1, FRODO, HDPR1, THYEX3
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(51339) Summary: The protein encoded by this gene belongs to the dapper family, characterized by the presence of PDZ-binding motif at the C-terminus. It interacts with, and positively regulates dishevelled-mediated signaling pathways during development. Depletion of this mRNA from xenopus embryos resulted in loss of notochord and head structures, and mice lacking this gene died shortly after birth from severe posterior malformations. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]
  • Mouse(59036) dapper homolog 1, antagonist of beta-catenin (xenopus)
  • Rat(500666) dishevelled-binding antagonist of beta-catenin 1
  • sheep(101116320) dapper, antagonist of beta-catenin, homolog 1 (Xenopus laevis)
  • dog(100687551) dapper, antagonist of beta-catenin, homolog 1 (Xenopus laevis)
  • naked mole-rat(101713951) dishevelled-binding antagonist of beta-catenin 1
  • cow(538778) dishevelled-binding antagonist of beta-catenin 1
  • domestic guinea pig(100728819) dishevelled-binding antagonist of beta-catenin 1
  • domestic cat(101098146) dapper, antagonist of beta-catenin, homolog 1 (Xenopus laevis)
  • Domestic Rabbit(100339172) dapper, antagonist of beta-catenin, homolog 1 (Xenopus laevis)
  • Zebrafish(405799) dapper homolog 1, antagonist of beta-catenin (xenopus)
  • chicken(723789) dapper, antagonist of beta-catenin, homolog 1 (Xenopus laevis)

Custom & Knockdown Gene Products

Antibodies

Numéro du produit
Description
Espèces réactives
Application
Anti-DACT1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry

western blot
Anti-DACT1 antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
bovine, human, mouse, pig, rat
Application
western blot
Anti-DACT1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry

esiRNA

Numéro du produit
Description
Espèce(s)
MISSION® esiRNA, targeting mouse Dact1,
Espèce(s)
mouse