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Merck

CYSLTR1

cysteinyl leukotriene receptor 1

Synonymes:
CYSLT1, CYSLT1R, CYSLTR, HMTMF81
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(10800) Summary: The cysteinyl leukotrienes LTC4, LTD4, and LTE4 are important mediators of human bronchial asthma. Pharmacologic studies have determined that cysteinyl leukotrienes activate at least 2 receptors, the protein encoded by this gene and CYSLTR2. This encoded receptor is a member of the superfamily of G protein-coupled receptors. Activation of this receptor by LTD4 results in contraction and proliferation of smooth muscle, oedema, eosinophil migration and damage to the mucus layer in the lung. [provided by RefSeq, Jul 2008]
  • Mouse(58861) cysteinyl leukotriene receptor 1
  • Rat(114099) cysteinyl leukotriene receptor 1
  • domestic cat(101087714) cysteinyl leukotriene receptor 1
  • chicken(428691) cysteinyl leukotriene receptor 1
  • Zebrafish(553675) cysteinyl leukotriene receptor 1
  • domestic guinea pig(100135514) cysteinyl leukotriene receptor 1
  • naked mole-rat(101713226) cysteinyl leukotriene receptor 1
  • cow(782045) cysteinyl leukotriene receptor 1
  • dog(100686426) cysteinyl leukotriene receptor 1
  • dog(608345) cysteinyl leukotriene receptor 1

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Small Molecule - Antagonist

Référence du produit
Description
Espèce(s)
Zafirlukast, ≥98% (HPLC),
Espèce(s)
human

Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-CYSLTR1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
western blot
Anti-CYSLTR1 antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human
Application
ELISA
immunofluorescence

western blot
Anti-CLTR1 antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human
Application
ELISA
immunofluorescence

western blot

Small Molecule - Ligand

Référence du produit
Description
Espèce(s)
Cinalukast, ~98% (HPLC),
Espèce(s)
human

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting mouse Cysltr1,
Espèce(s)
mouse
MISSION® esiRNA, targeting human CYSLTR1,
Espèce(s)
human